CAS No.29868-97-1,Pirenzepine hydrochloride Suppliers

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Basic Information

Molecular Structure:
CAS No.:	29868-97-1
Name:	Pirenzepine hydrochloride

Formula:	C₁₉H₂₁N₅O₂^.2(HCl)
Molecular Weight:	424.33
Synonyms:	6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-, dihydrochloride (8CI,9CI);5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride;Duogastral;Durapirenz;Gasteril;Gastricur;Gastrozepin;L-S 519;LS 519Cl2;LS 59Cl2;Leblon;Maghen;Pirenzepine dihydrochloride;Pirenzepinehydrochloride;Renzepin;Tabe;Ulcosan;Ulcuforton;
EINECS:	249-907-5
Density:	g/cm³
Melting Point:	248-250 °C
Boiling Point:	541.7 °C at 760 mmHg
Flash Point:	281.4 °C
Solubility:	50 mg/mL in water
Appearance:	white powder
PSA:	74.23000
LogP:	2.80740

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Chemistry

IUPAC Name: Pirenzepine hydrochloride
CAS: 29868-97-1
Formula: C₁₉H₂₃C_l2N₅O₂
Molecular Weight: 424.32
Molecular Structure of Pirenzepine hydrochloride (29868-97-1):

Flash Point: 281.4 °C
Melting Point: 248-250°C
Boiling Point: 541.7 °C at 760 mmHg
Appearance: white powder
Enthalpy of Vaporization: 81.97 kJ/mol
Vapour Pressure: 8.44E-12 mmHg at 25°C
Water Solubility: 50(mg/mL) at 25°C
Product Categories: all inhibitors;inhibitor;intermediates & fine chemicals;pharmaceuticals;acetylcholine receptor.

Toxicity Data With Reference

1.	orl-rat LD50:5 g/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),328.
2.	ipr-rat LD50:440 mg/kg	YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 23 (1981),1999.
3.	scu-rat LD50:3 g/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
4.	ivn-rat LD50:92 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
5.	orl-mus LD50:2600 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),328.
6.	ipr-mus LD50:407 mg/kg	DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),645.
7.	scu-mus LD50:2100 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
8.	ivn-mus LD50:96 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
9.	orl-rbt LD50:3000 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 9 (1975),377.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and HCl. See also DIAZEPAM.
Safety Information about Pirenzepine hydrochloride (29868-97-1):
WGK Germany: 2
RTECS: UU7883000

Specification

The chemical synonyms of Pirenzepine hydrochloride (29868-97-1) are 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6h-pyrido-[2,3-b][1,4] benzodiazepin-6-one dihydrobromide ; 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6h-pyrido-[2,3-b] [1,4]benzodiazepin-6-one dihydrochloride ; 5,11-Dihydro-11-[(4-methylpiperazin-1-yl)acetyl]-6h-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride ; Pirenzepine dihydrochloride ; Pirenzepine hcl hydrate ; Pirenzepine hydrochloride .It belongs to acid-suppressing drugs.It can be used in a variety of clinical acid-related disorders, such as: duodenal ulcer, gastric ulcer, stomach - esophageal reflux disease, high-acid gastritis, stress ulcer, acute gastric mucosal bleeding, gastrin tumors and so on.