Detail of "29899-95-4"

Reference

Sugar analogs as inhibitors of glycosylation

Sugar analogs as inhibitors of glycosylation. Bauer, C.; Kassuba, B.; Recktenwald, L.; Cerny, M.; Lehmann, J.; Reutter, W. (Inst. Molekularbiol., Freien Univ. Berlin, Berlin D-1000/33, Fed. Rep. Ger.). Falk Symp., Volume Date 1982, 34(Struct. Carbohydr. Liver), 527-37 (English) 1983. 2438-80-4 and 89157-32-4 which are cas registry numbers of chemicals are mentioned. CODEN: FASYDI. ISSN: 0161-5580. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 13 Different sugar analogs were tested for their ability to lower or block the formation of sugar nucleotides. The sugar analogs, esp. the furanose analog Clobenoside (I) [29899-95-4], could be suitable tools to elucidate the significance of the terminal sugars L-fucose [2438-80-4] and N-acetylneuraminic acid [131-48-6] in different glycoproteins and the function of protein-bound carbohydrates. The use of these sugar analogs in cancer chemotherapy is discussed. .

Protection against edema by clobenoside

Protection against edema by clobenoside. Hennings, G.; Felix, W.; Ruppert, R. (Med. Fak., Univ. Muenchen, Munich 8000/2, Fed. Rep. Ger.). Arzneim.-Forsch., 35(2), 498-500 (German) 1985. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Noninflammatory edema induced in the cat hind leg by the i.v. administration of ethacrynic acid was prevented by the prior administration of clobenoside (I) [29899-95-4]. I was equally effective whether given i.v. or orally, suggesting good oral bioavailability. I was also still highly active 24 h after a single oral dose, indicating a long half-life. I produced no cardiovascular side effects.