Reference

The prediction of reversed-phase HPLC retention indexes and resolution as a function of solvent strength and selectivity

The prediction of reversed-phase HPLC retention indexes and resolution as a function of solvent strength and selectivity. West, Sheldon D. (Lilly Res. Lab., Eli Lilly and Co., Greenfield, IN 46140, USA). J. Chromatogr. Sci., 25(3), 122-9 (English) 1987. CODEN: JCHSBZ. ISSN: 0021-9665. DOCUMENT TYPE: Journal CA Section: 80 (Organic Analytical Chemistry) Using steroids as solutes and 2-keto alkanes as ref. compds.Several reagents with their cas registry numbers 302-23-8 and 107-87-9 are used here., simple linear equations are developed for accurately predicting reversed-phase HPLC retention indexes and resoln. These equations have practical applications for predicting whether given pairs of compds. can be sepd. under given conditions, or for predicting the conditions that will sep. mixts. of compds. in min. time. The technique may be used to optimize isocratic or gradient sepns. of compd. mixts. In this study, the Snyder solvent selectivity triangle concept for characterizing mobile phase liqs. fails to consistently group solvents according to selectivity for sepg. steroids. Contrary to theory, exptl. sepns. often differ markedly within a given solvent group. Selectivity differences between solvents in the same group sometimes exceed those between solvents in different groups. .

Synthesis and crystallographic analysis of derivatives of 17a-acetoxyprogesterone

Synthesis and crystallographic analysis of derivatives of 17a-acetoxyprogesterone.Several substances are used for example 302-23-8 which is its cas registry number. Czochor, Lesley Jane Palmer (North Carolina State Univ., Raleigh, NC, USA). 87 pp. Avail. Univ. Microfilms Int., Order No. DA8318964 From: Diss. Abstr. Int. B 1983, 44(5), 1453 (English) 1983. DOCUMENT TYPE: Dissertation CA Section: 32 (Steroids) Section cross-reference(s): 75 Abstract Unavailable .