Reference

Fixation of steroids at the ends of poly(oxyethylene) chains

Fixation of steroids at the ends of poly(oxyethylene) chains. Chaabouni, Abdelaziz; Hubert, Patrick; Neel, Jean; Dellacherie, Edith (Lab. Chim.-Phys. Macromol., Ec. Natl. Super. Ind. Chim., Nancy, Fr.). C. R. Hebd. Seances Acad. Sci., Ser. C, 284(14), 521-3 (French) 1977. CODEN: CHDCAQ. DOCUMENT TYPE: Journal CA Section: 35 (Synthetic High Polymers) Section cross-reference(s): 32, 63 Polyethylene glycol (I) [25322-68-3] was hydrogenated, aminated, and condensed with carboxylic derivs. of steroids to give hydrophilic, biospecific materials suitable for affinity partitioning and other biol. applications. I was halogenated with SOCl2 or SOBr2 and the product was animated with NH3, MeNH2, PrNH2, or 1,3-diaminopropane. Steroid groups were covalently bonded at the terminal chain positions by reaction of the animated products with 3-(7-.alpha.-estradiol)butanoic acid [55592-40-0] or 3-keto-4-androstene-17,.beta.-carboxylic acid [302-97-6].

Hair tonics containing carpronium chloride and female hormones

Hair tonics containing carpronium chloride and female hormones. (Shiseido Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 59172412 A2 29 Sep 1984 Showa, 5 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K007-06. APPLICATION: JP 83-46934 19 Mar 1983. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 2 Hair tonics contain a mixt. of (1) carpronium chloride [13254-33-6], (2) female hormones such as ethynylestradiol [57-63-6], 17b-estradiol [50-28-2], estriol [50-27-1], and estrone [53-16-7], and (3) testosterone 5a-reductase [9036-43-5] inhibitors such as androstenedione [63-05-8], 4-androsten-3-one-17b-carboxylic acid [302-97-6], progesterone [57-83-0], corticosterone [50-22-6], and hydrocortisone [50-23-7]. Thus, a hair tonic comprises carpronium chloride 0.1, ethynylestradiol 0.005, 95% EtOH 70.0, hydrogenated ethoxylated castor oil 1.0, and deionized water 28.895% by wt.