Detail of "30418-59-8"

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CAS Number:
30418-59-8
Name:
Boronic acid,B-(3-aminophenyl)-
Superlist Name:
3-Aminobenzeneboronic acid
Molecular Structure:
Formula:
C₆H₈BNO₂
Molecular Weight:
136.9442
Synonyms:
Benzeneboronicacid, m-amino- (6CI,7CI,8CI);Boronic acid, (3-aminophenyl)- (9CI);3-Aminophenyl(dihydroxy)borane;m-Aminobenzeneboronic acid;m-Aminophenylboronicacid;
EINECS:
250-189-0
Density:
1.23 g/cm³
Melting Point:
98 °C
Boiling Point:
376 °C at 760 mmHg
Flash Point:
181.2 °C
Appearance:
light yellow crystalline solid
Hazard Symbols:
Xi
Risk Codes:
36/37/38
Safety:
26-36/37/39 Details

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Reference

Method for measuring the percentage of glycation of a protein: Method for measuring the percentage of glycation of a protein. Miyake, Takehiro; Tanaka, Kimikazu (Nacalai Tesque, Inc., Japan). Eur. Pat. Appl. EP 455225 A2 6 Nov 1991, 13 pp. DESIGNATED STATES: R: DE, FR, GB, IT, NL. (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: G01N033-68. ICS: G01N033-72. APPLICATION: EP 91-107023 30 Apr 1991. PRIORITY: JP 90-115547 1 May 1990. DOCUMENT TYPE: Patent CA Section: 9 (Biochemical Methods) A method is provided for measuring the percentage of glycation of a particular protein, which comprises the steps of contacting a sample contg.Several reagents with their cas registry numbers 30418-59-8 and 50-99-7 are used here. the particular protein with a solid phase of an antibody (or active fragments thereof) affixed to a support, the antibody having a specific affinity to the particular protein, thereby selectively binding the particular protein to the solid phase, sepg. the sample and solid phase, contacting a labeled boronic acid deriv. having affinity to glycated site of the particular protein, thereby binding a marker to the glycated site of the particular protein, then sepg. the solid and liq. phases of the reacted mixt., and measuring the amt. of the marker in the solid or liq. phase. This assay method permits measurement of the percentage of glycation of a particular protein in a simple operation, in a short period of time and accurately. The method may be used with samples of, e.g., blood or urine. Thus, glycated human serum albumin was prepd. and its percentage glycation detd. using polystyrene bead-immobilized antibody to human serum albumin and a peroxidase-labeled phenylboronic acid deriv. (std. curve included). Detn. of percentage of glycation of human Hb and of albumin in urine is also described. .

Investigations of the interaction between 3-aminophenylboronic acid and bovine serum albumin using fluorimetry: All Rights Reserved. Investigations of the interaction between 3-aminophenylboronic acid and bovine serum albumin using fluorimetry. Wang, Hua-Fang; Li, Wen-You; He, Xi-Wen; Chen, Lang-Xing; Zhang, Yu-Kui (Department of Chemistry, Nankai University, Tianjin 300071, Peop. Rep. China). Huaxue Xuebao, 65(1), 43-48 (Chinese) 2007 Huaxue Xuebao Bianjibu. CODEN: HHHPA4. ISSN: 0567-7351. DOCUMENT TYPE: Journal CA Section: 9 (Biochemical Methods) In order to understand the chem. mechanism and optimal conditions of the mol. imprinting, the interaction between 3-aminophenylboronic acid (APBA) and bovine serum albumin (BSA) was investigated using fluorescence quenching method with many factors, as the pH value, ionic strength and others, which maybe influence the interaction. The research results indicate that under appropriate ionic strength and pH 6.25, the fluorescence quenching shows that APBA strongly bound with the tryptophan of BSA, and the complex was formed with a molar ratio of 2: 1. Their apparent binding const. is KA = 1.0′1011 L2·mol-2, so their chem. bindings between donor BSA and acceptor APBA are relatively strong. According to the results, the interaction mechanism between APBA and BSA is predicted.In this experiment, several chemicals are used like 30418-59-8 and 73-22-3 During following research, it will be entirely possible to sep. or enrich BSA compn., maybe it could improve imprinting and eluting efficiency greatly. .

Detail of "30418-59-8"

Boronic acid,B-(3-aminophenyl)-

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CAS No.30418-59-8 3-Aminobenzeneboronic acid

CAS No.30418-59-8 3-Aminobenzeneboronic acid

Reference