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30433-91-1

Basic Information
CAS No.: 30433-91-1
Name: Thiophene-2-ethylamine
Article Data: 38
Molecular Structure:
Molecular Structure of 30433-91-1 (Thiophene-2-ethylamine)
Formula: C6H9NS
Molecular Weight: 127.21
Synonyms: 2-thiophen-2-ylethylazanium;2-Thiophene ethylamine;2-thiophen-2-ylethanamine;2-Thiopheneethylamine;2-thiophene ethyl amine;thiophene-2-ethylamine / 2-Thiophene ethylamine;Clopidogrel 2-(2-Thienyl)Ethyl Amine;
EINECS: 250-196-9
Density: 1.102 g/cm3
Melting Point: 202 °C
Boiling Point: 199.7 °C at 760 mmHg
Flash Point: 74.6 °C
Appearance: colorless to yellow liquid
Hazard Symbols: HarmfulXn,IrritantXi
Risk Codes: 20/21/22-36/37/38
Safety: 26-36-37/39
PSA: 54.26000
LogP: 1.94960
Synthetic route
874-84-0, 34312-77-1

2-(2-nitroethenyl)thiophene

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran Cooling with ice; Reflux;92%
With lithium aluminium tetrahydride In tetrahydrofuran Reflux; Cooling with ice;92%
With lithium aluminium tetrahydride In tetrahydrofuran Cooling with ice; Reflux;92%
149551-70-2

2-(2-azidoethyl)thiophene

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In methanol at 20℃; for 16h;100%
With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; tri-n-butyl-tin hydride In tetrahydrofuran at 0℃; for 0.5h; Reduction;89%
20893-30-5

2-cyanomethylthiophene

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With indium(III) chloride; sodium tetrahydroborate In tetrahydrofuran at 25℃; for 4h; Inert atmosphere;98%
With lithium aluminium tetrahydride In tetrahydrofuran71%
With lithium aluminium tetrahydride; aluminium trichloride In diethyl ether for 1h; Ambient temperature;56%
26359-22-8

3-(thiophen-2-yl)-propionamide

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With sodium hydroxide; sodium hypochlorite Zusatz von Kaliumhydroxid;
With bromine at 70℃; for 1h; Hofmann Rearrangement; Large scale;1110g
4461-29-4

2-(thiophen-2-yl)acetamide

54903-50-3

4,5,6,7-tetrahydrothieno[3,2-c]pyridine

2-(2-thienyl)ethylimide

2-(2-thienyl)ethylimide

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
In hydrogenchloride; sodium hydroxide74.5%
34312-77-1

1-(2-thienyl)-2-nitroethene

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With diborane
With hydrogenchloride; sodium borohydrid; trifluoroborane diethyl ether In tetrahydrofuran; water; toluene
123-54-6

acetylacetone

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With sodium carbonate In 2-methoxy-ethanol; water

C7H10N2OS

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With bromine at 60℃; for 1h; Hofmann Rearrangement;
59594-93-3

4-(thiophen-2-yl)butan-2-one

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With hydrogen azide at 60 - 120℃;
30807-46-6

2-(2-nitroethyl)thiophene

30433-91-1

[2-(2-thyenyl)ethyl]amine

Conditions
ConditionsYield
With hydrogen at 120℃; for 12h; Autoclave;1009 g
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    Thiophene-2-Ethylamine CAS NO.: 30433-91-1 Formula: C6H9NS Molecular Weight: 127.21 Characteristic: It is clear colorless to light brown liquid. Usage: It is mainly used for synthetic thiophene pyridine and clopidogrel intermediate.

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    Product name: Thiophene-2-Ethylamine CAS No.: 30433-91-1 Molecule Formula:C6H10NS Molecule Weight:128.21 Purity: 98.0% Package: 25kg/drum Description:White to off-white powder Manufacture Standards:Enterprise Standard

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  • Thiophene-2-ethylamine CAS NO.30433-91-1 CAS NO.30433-91-1  CAS NO.30433-91-1

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    Thiophene-2-ethylamine CAS NO.30433-91-1 CAS NO.30433-91-1 CAS NO.30433-91-1

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Chemistry

The Molecular Structure of Thiophene-2-ethylamine (CAS NO.30433-91-1):

Empirical Formula: C6H9NS
Molecular Weight: 127.2074 
IUPAC Name:  2-thiophen-2-ylethanamine 
Appearance: colorless to yellow liquid
Nominal Mass: 127 Da
Average Mass: 127.2074 Da
Monoisotopic Mass: 127.045569 Da 
Index of Refraction: 1.567
Molar Refractivity: 37.72 cm3
Molar Volume: 115.4 cm3
Surface Tension: 43.3 dyne/cm
Density: 1.102 g/cm3
Flash Point: 74.6 °C
Enthalpy of Vaporization: 43.59 kJ/mol
Boiling Point: 199.7 °C at 760 mmHg
Vapour Pressure: 0.337 mmHg at 25°C 
Storage temp: Refrigerator (+4°C)
Sensitive: Air Sensitive
InChI
InChI=1/C6H9NS/c7-4-3-6-2-1-5-8-6/h1-2,5H,3-4,7H2
Smiles
s1c(ccc1)CCN 
Product Categories: Anilines, Aromatic Amines and Nitro Compounds;Thiophene&Benzothiophene;Amines;Heterocyclic Compounds;Ticlopidine Clopidogrel;Building Blocks;Heterocyclic Building Blocks;Thiophenes

Uses

 Thiophene-2-ethylamine (CAS NO.30433-91-1) can be used for intermediates of the drug CLOPIDOGREL and General organic synthesis.

Safety Profile

Hazard Codes: IrritantXiHarmfulXn
Risk Statements 
  R20/21/22-36/37/38 ( Harmful by inhalation, in contact with skin and if swallowed ;Irritating to eyes, respiratory system and skin )
Safety Statements 
  S26-36-37/39 (In case of contact with eyes, rinse immediately with plenty of WATER and seek medical advice;Wear suitable protective clothing;Wear suitable gloves and eye/face protection)
WGK Germany: 3
HazardClass: IRRITANT

Specification

 Thiophene-2-ethylamine (CAS NO.30433-91-1) is also called as Thiophene ethylamine ; Thiophene-2-ethylamine hcl salt ; 2-(2-Aminoethyl)thiophene ; 2-(2'-Thienyl)ethyl amine ; 2-(2-Thienyl)ethylamine ; 2-(2-Thienyl)-1-ethanamine .