Products Categories
| CAS No.: | 305-85-1 |
|---|---|
| Name: | 2,6-Diiodo-4-nitrophenol |
| Article Data: | 39 |
| Molecular Structure: | |
|
|
|
| Formula: | C6H3I2NO3 |
| Molecular Weight: | 390.904 |
| Synonyms: | 4-Nitro-2,6-diiodophenol;Ancylol;Disofen;Disophenol;Iodofen;Iodophen;Syngamix; |
| EINECS: | 206-170-4 |
| Density: | 2.717 g/cm3 |
| Melting Point: | 152-154 °C(lit.) |
| Boiling Point: | 310.6 °C at 760 mmHg |
| Flash Point: | 141.6 °C |
| Solubility: | very sparingly soluble in water |
| Appearance: | yellow crystalline solid |
| Hazard Symbols: |
 Xn,  T
|
| Risk Codes: | 20/21/22-36/37/38-25 |
| Safety: | 26-28-36/37/39-45-28A |
| Transport Information: | UN 2811 6.1/PG 3 |
| PSA: | 66.05000 |
| LogP: | 3.03280 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
| Conditions | Yield |
|---|---|
| With hydrogenchloride; potassium iodate; potassium iodide In methanol; water at 20℃; | 99% |
| With sodium periodate; sulfuric acid; iodine; potassium iodide; sodium sulfite In water; acetic acid at 25℃; for 4h; | 98% |
| With N-iodo-S-methyl-S-phenyl sulfoximine; acetic acid at 22℃; for 3h; Sealed tube; | 98% |
| Conditions | Yield |
|---|---|
| With iodine; silver sulfate In ethanol at 20℃; for 0.5h; | A 22% B 50% |
| With sulfuric acid; dihydrogen peroxide; potassium iodide In methanol at 60℃; for 2h; | A 18% B 42% |
| With iodine; silver nitrate In acetonitrile for 2h; Ambient temperature; | A 5% B 12% |
| Conditions | Yield |
|---|---|
| With sodium nitrite |
| Conditions | Yield |
|---|---|
| With acetic acid; sodium nitrite; benzene Trennung durch fraktionierte Krystallisation der Kaliumsalze; | |
| With acetic acid; sodium nitrite; benzene |
| Conditions | Yield |
|---|---|
| With ethanol; iodine; mercury(II) oxide |
| Conditions | Yield |
|---|---|
| With iodine; mercury(II) oxide |
- 96-97-9
5-nitrosalicylic acid
A
- 305-85-1
2,6-diiodo-4-nitrophenol
B
- 861565-06-2
2-hydroxy-3-iodo-5-nitro-benzoic acid
| Conditions | Yield |
|---|---|
| With ethanol; iodine; mercury(II) oxide |
- 28177-54-0
2,6-diiodo-phenol
- 305-85-1
2,6-diiodo-4-nitrophenol
| Conditions | Yield |
|---|---|
| durch Nitrierung; |
| Conditions | Yield |
|---|---|
| With nitric acid |
- 16825-79-9
1-iodyl-4-nitrobenzene
- 305-85-1
2,6-diiodo-4-nitrophenol
| Conditions | Yield |
|---|---|
| With sodium nitrite | |
| With sodium azide |
What can I do for you?
Get Best Price
Chemistry
Empirical Formula: C6H3I2NO3 
Molecular Weight: 390.9019
IUPAC Name: 2,6-Diiodo-4-nitrophenol
Synonyms: Phenol, 2,6-diiodo-4-nitro- ; Disofen ; Diisophenol ; Ancylol
Melting Point: 152-154 °C(lit.)
Flash Point: 141.6 °C
Boiling Point: 310.6 °C at 760 mmHg
Density of 2,6-Diiodo-4-nitrophenol (305-85-1): 2.717 g/cm3
Vapour Pressure: 0.000325 mmHg at 25°C
Index of Refraction: 1.782
Water Solubility: 2,6-Diiodo-4-nitrophenol (305-85-1) is very sparingly soluble
Sensitive: Light Sensitive
Stability: 2,6-Diiodo-4-nitrophenol (305-85-1) is stable.
Appearance: 2,6-Diiodo-4-nitrophenol (305-85-1) is a yellow crystalline solid
Uses
2,6-Diiodo-4-nitrophenol (305-85-1) is used against hookworm.
Toxicity Data With Reference
| 1. | orl-rat LD50:170 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 2. | ipr-rat LD50:105 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 3. | scu-rat LD50:122 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 4. | ivn-rat LD50:105 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 5. | orl-mus LD50:212 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 6. | ipr-mus LD50:107 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 7. | scu-mus LD50:110 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 8. | ivn-mus LD50:88 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 6 (1964),232. | ||
| 9. | par-uns LDLo:36 mg/kg | FAZMAE Fortschritte der Arzneimittelforschung. 17 (1973),108. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, intravenous, and parenteral routes. An anthelmintic. When heated to decomposition it emits very toxic fumes of I− and NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.
Safety: DANGER: POISON, causes cyanosis; skin, eye, lung irritation. Safety glasses, good ventilation.
Hazard Codes: Xn: Harmful 
,
T: Toxic 
Risk Statements: 20/21/22: Harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
25: Toxic if swallowed
Safety Statements: 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: SL0750000
HazardClass: 6.1
PackingGroup: III
Specification
2,6-Diiodo-4-nitrophenol (305-85-1) is a yellow crystalline solid used against hookworm. It is a halogenated and nitrated phenol. Reacts as a weak acid. It is stable and very sparingly soluble in water.