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Detail of "30516-87-1"

  • MSDS Download
  • CAS Number:
  • 30516-87-1
  • Name:

  • Thymidine,3'-azido-3'-deoxy-

  • Superlist Name:
  • Zidovudine
  • Molecular Structure:
  • Formula:
  • C10H13N5O4
  • Molecular Weight:
  • 267.24
  • Deleted CAS:
  • 399024-19-2
  • Synonyms:
  • 3-Azido-3-deoxythymidine;3'-Azido-3'-deoxythymidine;3'-Azidothymidine;3'-Deoxy-3'-azidothymidine;AZT;AZT (pharmaceutical);Azidothymidine;Azitidin;BW-A 509U;Compound S;NSC602670;Retrovir;Retrovir IV;Retrovis;Timazid;Viro-Z;ZDV;ZVD;Zido-H;
  • Melting Point:
  • 106-112 °C
  • Solubility:
  • 1-5 g/100 mL at 17 °C in water
  • Appearance:
  • Off -white crystalline powder
  • Hazard Symbols:
  • HarmfulXn
  • Risk Codes:
  • 40-36/37/38-20/21/22
  • Safety:
  • 36/37/39-45-36-26 Details
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CAS No.30516-87-1 ZidovudineCompetitive Product

Molecular Formula: C10H13N5O4 Molecular Weight: 267.25 Specification: USP It is used for the treatment of HIV.

Supplier:Xinchang Yueding Chemical Co., Ltd. [ China (Mainland)]

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CAS No.30516-87-1 ZidovudineCompetitive Product

Zidovudine,Cas#30516-87-1

Supplier:Frapp's Chemical (NFTZ) Co.,Ltd [ China (Mainland)]

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CAS No.30516-87-1 ZidovudineCompetitive Product

  Appearance:white powder

Supplier:Wenling Imp. & Exp. Co.,Ltd. [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

Assay:99%  Appearance:powder  Package:25kg/drum

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CAS No.30516-87-1 Zidovudine

  Appearance:Needle cryst...Storage:20°C  Transportation:sea trans...  Application:Used as anti...

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CAS No.30516-87-1 Zidovudine

Assay:USP32/EP6  Package:25kg/drum

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CAS No.30516-87-1 Zidovudine

Assay:99%  Appearance:White to off...

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CAS No.30516-87-1 Zidovudine

--Product Name: Zidovudine --Category:Intermediates --CAS NO:30516-87-1 --MF:C10H13N5O4 --MW:267.24 --InChI:InChI=1/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1 --Synonyms:3-Azido-3-deoxy-thymidine;azidoth

Supplier:Shenyang Meiyao Chemical Co., Ltd., [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

30516-87-1

Supplier:Jinan Wedo Industrial Co., Ltd. [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Zidovudine

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CAS No.30516-87-1 Zidovudine

Zidovudine

Supplier:ZHEJIANG HOLYPHARM BIOTECH CO.,LTD [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Assay:98%

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CAS No.30516-87-1 Zidovudine

3-Azido-3-deoxythymidine

Supplier:Spectrum China Ltd. [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

zidovudine---We supply this product in very competitive price.

Supplier:Hangzhou UNIWISE International Co.,Ltd. [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Zidovudine

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CAS No.30516-87-1 Zidovudine

Supplier:LIDE PHARMACEUTICALS LIMITED [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

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CAS No.30516-87-1 Zidovudine

Assay:99%min  Appearance:White crysta...  Package:1kg/bag, 25k...Storage:kept in a co...  Transportation:Keep away fr...  Application:Pharmaceutic...

Min. Order:50Gram

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CAS No.30516-87-1 Zidovudine

Assay:above 98%  Appearance:white crysta...  Package:25kg/fibre d...

product name:zidovudine CAS NO.:30516-87-1 Mol Fm:C10H12N2O4 Mol Wt:224.22 Application:Melting Point:159-160℃ Assay:>=99.0% Package: 1KG 5KG 25KG Storage:Cool and arid place,far awary from fire

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CAS No.30516-87-1 Zidovudine

Quick Details CAS No.: 30516-87-1 Other Names: Azidothymidine MF: C10H13N5O4 Place of Origin: China (Mainland) Type: Antivirus Brand Name: ICH Purity: 99% Product: Zidovudine

Supplier:handan yushuo chem co.，ltd [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Supplier:HONGKONG CHEMAPI LIMITED [ Hong Kong]

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CAS No.30516-87-1 Zidovudine

USP30

Supplier:TAIZHOU SHASIN PHARMACHEM CO.,LTD [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Zidovudine USP31

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CAS No.30516-87-1 Zidovudine

Zidovudine

Supplier:Zhejiang Chemicals Import & Export Corporation (ZHECHEM) [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

Assay:99.0%min  Appearance:white powder

Common Name: Zidovudine Chemical Name: 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione Molecular Formula: C10H13N5O4 Molecular Weight: 267.24 Specific Rotation: +60.5~+63 Specification: USP Melting point: 106-112 oC

Supplier:Tomson Chemical Co., LTD. [ China (Mainland)]

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CAS No.30516-87-1 Zidovudine

3'-AZIDO-3'-DEOXYTHYMIDINE

Supplier:Waterstone Technology, LLC [ United States]

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CAS No.30516-87-1 Zidovudine

1) USP28 2) Molecular formula: C10H13N5O4 3) CAS: 30516-87-1 USP28Outer packing:25kg/drumA dideoxynucleoside compound in which the 3-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkage

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CAS No.30516-87-1 Zidovudine

[Molecular Formula] C10H13N5O4 [Molecular Weight] 267.25 [Specification] USP [Uses] It is used for the treatment of HIV.

Supplier:Zhejiang Xinhua Pharmaceutical Co., Ltd. [ China (Mainland)]

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Reference

In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates. Uckun, Fatih M.; Pendergrass, Sharon; Qazi, Sanjive; Venkatachalam, Taracad K. (Drug Discovery Program, Departments of Virology, Bioinformatics, Immunology, and Chemistry, Parker Hughes Cancer Center, St. Paul, MN, USA). Arzneimittel Forschung, 54(1), 69-77 (English) 2004 Editio Cantor Verlag. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The in vitro activity profile of stampidine (CAS 217178-62-6, STAMP) was examd. against clin. isolates of HIV-1. In a side-by-side comparison against 10 zidovudine-sensitive clin. HIV-1 isolates, STAMP was 100-fold more potent than stavudine (CAS 3056-17-5) and twice as effective as zidovudine (CAS 30516-87-1). STAMP was also active against phenotypically and/or genotypically NRTI (nucleoside analog inhibitors of reverse transcriptase)-resistant HIV and inhibited the replication of 20 zidovudine-resistant clin. HIV-1 isolates with low nanomolar to subnanomolar IC50 values. Similarly, STAMP inhibited the replication of 9 genotypically NNRTI (non-nucleoside analog inhibitors of reverse transcriptase)-resistant clin. HIV-1 isolates (n = 9) with an av. IC50 value of 11.2 ± 6.5 nmol/L. The remarkable potency of STAMP against clin. HIV-1 isolates with NRTI- or NNRTI-resistance warrants the further development of this promising new antiviral agent.
Synthesis and biological activity of several amino analogs of thymidine
Synthesis and biological activity of several amino analogs of thymidine. Lin, Tai-Shun; Prusoff, William H. (Dep. Pharmacol., Yale Univ. Sch. Med., New Haven, Conn., USA). J. Med. Chem., 21(1), 109-12 (English) 1977. CODEN: JMCMAR. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 33 Tosylation of 3'-azido-3'-deoxythymidine [30516-87-1] followed by reaction with LiN3 and hydrogenation gave 3',5'-diamino-3',5'-dideoxythymidine (I) [64638-15-9], while hydrogenation of 3'-azido-3'-deoxythymidine gave 3'-amino-3'-deoxythymidine (II) [52450-18-7]. Thymidine [50-89-5] was selectively tosylated in the 5' position and reaction with LiN3 and hydrogenation gave 5'-amino-5'-deoxythymidine (III) [25152-20-9]. III has potent antiviral activity but is a poor antineoplastic agent; II is a potent inhibitor of replication of murine sarcoma 180 cells and murine L1210 cells in vitro but is a poor antiviral agent, while I has neither antiviral nor antineoplastic activity. Structure-activity relations are discussed. Of various nucleosides tested, only the pyrimidine deoxyribonucleosides were effective in preventing inhibition of L1210 cells by II.
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