CAS No.31282-04-9,Hygromycin B Suppliers,MSDS download

Products Categories

Pharmaceutical (93)
Organic Chemicals (24)
Others (23)
Reagent (11)
Plant Extract (2)
Agrochemicals (1)
(1)
Synthetic Flavours & Fragrances (1)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	31282-04-9
Name:	Hygromycin B

Formula:	C₂₀H₃₇N₃O₁₃
Molecular Weight:	527.526
Synonyms:	HygromycinB (7CI);Antihelmycin;Hygromix 2.4;Hygromix-8;Hygrovetin;Hygrovetine;
EINECS:	250-545-5
Density:	1.67 g/cm³
Melting Point:	160-180 °C
Boiling Point:	897.6 °C at 760 mmHg
Flash Point:	496.7 °C
Solubility:	Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.
Appearance:	Amorphous solid or tan powder.
Hazard Symbols:	T+, Xn
Risk Codes:	26/27/28-41-42/43-40
Safety:	23-26-28-36/37/39-45-22-36
Transport Information:	UN 3462 6.1/PG 1
PSA:	272.06000
LogP:	-5.47910

Total:124 Page 1 of 4 1 2 3 4 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 31282-04-9

Specification

The Hygromycin B , with cas registry number of 31282-04-9, also has other registry numbers which are 1403-76-5, 8052-92-4, 8052-93-5. It is also called for Hygrovectine ; Hygromix-8 ; Antihelmycin ; Hygrovetine , and O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-o-beta-D-talopyranosyl-(1-5)-2-deoxy-N3-methyl-D-streptamine . Hygromycin B is from streptomyces hygroscopicus. It belongs to the categories of (1) Anthelmintics ; (2) Anti-Bacterial Agents ; (3) Anti-Infective Agents ; (4) Antiparasitic Agents ; (5) Drug / Therapeutic Agent ; (6) Natural Product.

Physical properties of Hygromycin B : (1) ACD/LogP: 0.64 ; (2) # of Rule of 5 Violations: 3 ; (3) ACD/LogD (pH 5.5): -4.36 ; (4) ACD/LogD (pH 7.4): -2.58 ; (5) ACD/BCF (pH 5.5): 1 ; (6) ACD/BCF (pH 7.4): 1 ; (7) ACD/KOC (pH 5.5): 1 ; (8) ACD/KOC (pH 7.4): 1 ; (9) #H bond acceptors: 16 ; (10) #H bond donors: 13 ; (11) #Freely Rotating Bonds: 16 ; (12) Index of Refraction: 1.672 ; (13) Molar Refractivity: 118.04 cm³ ; (14) Molar Volume: 315.1 cm³ ; (15) Surface Tension: 103.2 dyne/cm ; (16) Enthalpy of Vaporization: 148.17 kJ/mol.

Uses of Hygromycin B : Hygromycin B , very safe de-worming drug, can effectively kill the roundworm of pigs, whipworm and chickens' roundworm, and have antibacterial effect. And it also can be used for chicken feed (the dosage of 8 (800 × 104U)-12 (1200 × 104U) g / t, Laying disabled, withdrawal period 3 days) and the following 4-month-old pig feed (the dosage of 10 -- 13g / t, withdrawal period of 15 days, to avoid eye contact with human skin).

When you are using this chemical, please be cautious about it as the following:
The Hygromycin B is very toxic by inhalation, in contact with skin and if swallowed. It may cause sensitization by inhalation and skin contact. It has risk of serious damage to the eyes and limited evidence of a carcinogenic effect. Before use it, wear suitable protective clothing, gloves and eye/face protection. Do not breathe vapour and dust. If contact with eyes, rinse immediately with plenty of water and seek medical advice. In case of feel unwell, seek medical advice immediately. It is a poison by intraperitoneal route. When heated to decomposition, it emits toxic fumes of NO_x.

You can still convert the following datas into molecular structure:
(1)SMILES:O1[C@H]4[C@@H](OC12O[C@@H]([C@H](O)[C@@H](O)[C@H]2O)[C@@H](N)CO)[C@@H](O)[C@H](O[C@H]4O[C@@H]3[C@@H](O)[C@H](N)C[C@H](NC)[C@H]3O)CO;
(2)InChI:InChI=1/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13-,14-,15-,16+,17+,18-,19+,20?/m1/s1;
(3)InChIKey:GRRNUXAQVGOGFE-KPBUCVLVBD

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intraperitoneal	13mg/kg (13mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(5), Pg. 11, 1973.
mouse	LD50	intravenous	6mg/kg (6mg/kg)		"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 1, Pg. 202, 1980.
mouse	LD50	oral	46000units/kg (46000units/kg)		Pharmaceutical Chemistry Journal Vol. 1, Pg. 396, 1967.
mouse	LDLo	intraperitoneal	6mg/kg (6mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Journal of Pharmacology and Experimental Therapeutics. Vol. 281, Pg. 992, 1997.
rat	LC50	inhalation	2220ug/m³/4H (2.22mg/m³)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE BEHAVIORAL: AGGRESSION	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(5), Pg. 11, 1973.
rat	LD50	intraperitoneal	63mg/kg (63mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(5), Pg. 11, 1973.