Reference

Perspiration regulating compositions

Perspiration regulating compositions. Olivier, Georges Remy Gaston (Fr. ). Eur. Pat. Appl. EP 91368 A2 12 Oct 1983,12 pp. DESIGNATED STATES: R: BE, CH, DE, FR, GB, IT, LI. (French). (European Patent Organization). CODEN: EPXXDW. CLASS: IC: A61K007-32.In this article, certain chemicals are used. Some of their cas registry numbers are 95-27-2 and 557-04-0 APPLICATION: EP 83-400671 31 Mar 1983. PRIORITY: FR 82-5898 1 Apr 1982. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Perspiration regulating compns. contain a mixt. of at least 1 antiabsorbant, antiseptic, antisudorific, antimycotic, anti-irritant, antifungal, emollient, astringent and(or) narcotic. A formulation consists of Me p-hydroxybenzoate [99-76-3] 0.07, Pr p-hydroxybenzoate [94-13-3] 0.05, Bu p-hydroxybenzoate [94-26-8] 0.03, benzoic acid [65-85-0] 2, tannic acid 2, K alum 10, ZnO 5, kaolin 34, starch [9005-25-8] 5, MgO (slightly calcined) 8, talc 20, Mg stearate [557-04-0] 5, allantoin [97-59-6] 2, a-ketoglutaric acid [328-50-7] 0.85 and chlorhydrol [1327-41-9] 6%. The compn. may be in the form of powder, cream, stick, etc. .

Amino acid uptake, content, and metabolism by neuronal and glial enriched cellular fractions from mouse cerebellum

Amino acid uptake, content, and metabolism by neuronal and glial enriched cellular fractions from mouse cerebellum. Shank, Richard P.; Campbell, Graham LeM. (Dep. Neurol., Grad. Hosp., Philadelphia, PA 19146, USA). J. Neurosci., 4(1), 58-69 (English) 1984. CODEN: JNRSDS. ISSN: 0270-6474. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Section cross-reference(s): 13 Cerebellar tissue from 8-14-day-old mice was dissocd. by mild trypsinization and mech. agitation and the dissocd. cellular material was sepd. into 5 fractions using a series of continuous d. gradients formed with Percoll. Of 3 fractions comprised primarily of cell bodies, 1 was dominated by cells having the size and morphol. appearance of granule cells and the other 2 were enriched in astrocyte cell bodies. The remaining 2 fractions were enriched, resp., in nerve terminals and large nucleated cell bodies. The uptakes of amino acids and other metabolites by these cellular fractions were examd., and Km and Vmax values were detd. High affinity transport carriers (Km ~ 1-20 mM) for most of the compds. studied were evident in the astrocyte-enriched fractions; however, for glutamate [56-86-0] and GABA [56-12-2] addnl. carriers with higher substrate affinities (Km, 0.1-0.3 mM) were evident in the astrocyte-enriched fraction. The fraction enriched in granule cell bodies had an exceptionally low uptake of GABA and citrate [77-92-9], and a comparatively low uptake of b-alanine [107-95-9], taurine [107-35-7], a-ketoglutarate [328-50-7], and glutamate. Glutamate, aspartate [56-84-8], and GABA were the only amino acids concd. in the fraction enriched in nerve terminals. GABA was concd. also in the fraction enriched in large cell bodies and was present at a low concn. in the fraction enriched in granule cell bodies. The other amino acids were distributed nearly evenly among the 5 fractions. Several differences in metabolic activity among the fractions were obsd. 56-41-7 and 107-35-7 are just another two chemicals used in this study. Radiolabel from several precursors was incorporated into GABA preferentially in the fractions enriched in large cell bodies and nerve terminals. In contrast, the accumulation of label into glutamine occurred preferentially in the fractions enriched in astrocytes and granule cell bodies. Labeling of alanine from [14C]pyruvate and of proline from [14C]ornithine was most prominent in the fractions enriched in astrocytes and granule cell bodies. .