Reference

Pharmaceutical composition with psychotropic action

Pharmaceutical composition with psychotropic action. (Science Union et Cie.-Societe Francaise de Recherche Medicale, Fr.). Ger. Offen. DE 2639575 9 Mar 1978, 23 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: A61K031-51. APPLICATION: DE 76-2639575 2 Sep 1976. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Psychoanaleptic tablets, suppositories or parenteral solns. comprise 150-500 mg vitaberin (I) [3286-46-2]/dosage unit. For example, 0.525 g tablets each contg. 400 mg I were prepd. from a mixt. comprising I 4050, cornstarch 200, Na CM-cellulose 100, white wax 100, dried starch paste 50, ethyl cellulose 50, glucose 50, lactose 250, yellow-orange lacquer S 100, Mg stearate 200, polyoxyethylene sorbate 40, poly(vinylpyrrolidone) 50, SiO2 50, and white sugar 30 g.

Pharmaceutical compositions and method for treating psychasthenia

Pharmaceutical compositions and method for treating psychasthenia. Servier, Jacques (Science Union et Cie.-Societe Francaise de Recherche Medicale, Fr.). U.S. US 4071629 31 Jan 1978, 4 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-505. NCL: 424251000. APPLICATION: US 76-718134 27 Aug 1976. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Psychotropic compns. contg. vitaberin (I) [3286-46-2] are prepd. and used in the treatment of psychic and/or behavioral disturbances due to psychasthenia at dosages of 3.3-25 mg/kg/day. For example, suppositories were formulated comprising I 415, polyethylene glycol stearate 400, cocoa butter 1850, and canthaxanthine 0.5 g for 1000 2.75 g suppositories. In av. daily oral dosage of 600 mg for ~4 wk resulted in improvement of the memory, attentiveness, ideation and vigilance in 37 patients out of 46.