Detail of "3289-47-2"

CAS Number:
3289-47-2
Name:
4-Pyrimidinamine,2-methoxy-
Molecular Structure:
Formula:
C₅H₇N₃O
Molecular Weight:
125.12858
Synonyms:
Pyrimidine,4-amino-2-methoxy- (6CI,7CI,8CI);2-Methoxy-4-pyrimidinamine;2-Methoxycytosine;2-O-Methylcytosine;4-Amino-2-methoxypyrimidine;
Density:
1.224 g/cm³
Boiling Point:
294.4 °C at 760 mmHg
Flash Point:
131.9 °C

Display：

Supplier:RennoTech Co., Ltd. [ China (Mainland)]

Integral
16

Tel:Tel: +86-25-58353800, Fax: +86-25-58353700

Address:23 Lijing Road, Nanjing Hi-Tech Zone, Nanjing, Jiangsu, China, 210061

Supplier:Shanghai Foucs Chemical Co., Ltd [ China (Mainland)]

Integral
10

Tel:86-021-50812725

Address:shanghai

670 Integral
670

Tel:+86-570-3081766

Address:Room 624A No.58, Liangguan Rd, Fangshan, Beijing, China

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli: Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli. McCarthy, T. V.; Karran, P.; Lindahl, T. (Mill Hill Lab., Imp. Cancer Res.There are some reagents with their cas registry numbers 3289-47-2 and 9037-42-7 are used in this study. Fund, London NW7 1AD, UK). EMBO J., 3(3), 545-50 (English) 1984. CODEN: EMJODG. ISSN: 0261-4189. DOCUMENT TYPE: Journal CA Section: 10 (Microbial Biochemistry) The 3 miscoding alkylated pyrimidines O2-methylcytosine, O2-methylthymine and O4-methylthymine are specifically recognized by E. coli DNA repair enzymes. The activities are induced as part of the adaptive response to alkylating agents. O2-Methylcytosine and O2-methylthymine are removed by a DNA glycosylase, the alkA+ gene product, which also acts on N3-methylated purines. O4-Methylthymine is repaired by a methyltransferase, previously known to correct O6-methylguanine by transfer of the Me group to one of its own cysteine residues. It is proposed that certain common structural features of the various methylated bases allow each of the 2 inducible repair enzymes to recognize and remove several different kinds of lesions from alkylated DNA. .