Detail of "3344-77-2"

Reference

A simple synthesis of 1-triacontanol

A simple synthesis of 1-triacontanol. Kulkarni, S. M.; Mamdapur, V. R.; Chadha, M. S. (Bio-Org. Div., Bhabha At. Res. Cent., Bombay 400 085, India). Indian J. Chem., Sect. B, 22B(7), 683 (English) 1983. CODEN: IJSBDB. ISSN: 0376-4699. DOCUMENT TYPE: Journal CA Section: 26 (Biomolecules and Their Synthetic Analogs) 1-Triacontanol was efficiently prepd. by coupling Me(CH2)17MgBr with 12-bromo-1-tetrahydropyranyloxydodecane in the presence of Li2CuCl4, followed by acid hydrolysis of the coupled product.Except for chemicals metioned above, 593-50-0 and 3344-77-2 are also used. .

Detection of transmembrane potentials by optical methods

Detection of transmembrane potentials by optical methods. Tsien, Roger Y.; Gonzalez, Jesus E., III (Regents of the University of California; Tsien, Roger Y.; Gonzalez, Jesus, E. III, USA). PCT Int. Appl. WO 9641166 A2 19 Dec 1996, 112 pp. DESIGNATED STATES: W: AL, AM, AT, AU, AZ, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, NL, PT, SE. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: G01N033-50. ICS: G01N033-52; C07D239-60; C07D209-08; C07F005-00; C07F005-02. APPLICATION: WO 1996-US9652 6 Jun 1996. PRIORITY: US 1995-481977 7 Jun 1995. DOCUMENT TYPE: Patent CA Section: 9 (Biochemical Methods) Section cross-reference(s): 1, 6, 73 Methods and compns. are provided for detg. 3344-77-2 and 158920-76-4 which are cas registry numbers of chemicals are mentioned. the potential of a membrane. In one aspect, the method comprises: (1) introducing a first reagent comprising a hydrophobic fluorescent ion capable of redistributing from a first face of the membrane to a second face of the membrane in response to changes in the potential of the membrane, as described by the Nernst equation; (2) introducing a second reagent which labels the first face or the second face of the membrane, which second reagent comprises a chromophore capable of undergoing energy transfer by either donating excited state energy to the fluorescent ion or accepting excited state energy from the fluorescent ion; (3) exposing the membrane to radiation; (4) measuring energy transfer between the fluorescent ion and the second reagent; and (5) relating the energy transfer to the membrane potential. Energy transfer is typically measured by fluorescence resonance energy transfer. In some embodiments the first and second reagents are bound together by a suitable linker. In one aspect, the method is used to identify compds. which modulate membrane potentials in biol. membranes. .