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CAS No.: | 33515-09-2 |
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Name: | Gonadorelin |
Article Data: | 23 |
Molecular Structure: | |
Formula: | C55H75N17O13 |
Molecular Weight: | 1182.31 |
Synonyms: | Glycinamide,5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolyl-(8CI);Luteinizing hormone-releasing factor (pig);AY 24031;Dirigestran;Fertagyl;Gonadotropin-releasing factor;HOE 471;HumanLH-RH;LH-RH (swine);LH-Releasing factor (pig);LH-Releasinghormone (porcine);Lutal;Luteinizing hormone-releasingfactor (human);Luteinizing hormone-releasing hormone (swine);Lutrefact;Mammalian LH-RH;Ovine gonadotropin-releasing hormone;Porcine LH-releasing factor;Relefact;Relisorm L;Synthetic Gn-RH;SyntheticLH-FSH releasing hormone;Synthetic LH-FSH-RH;Synthetic LH-RH/FSH-RH;Synthetic LH-releasing factor;Synthetic LRF;Synthetic decapeptide FSH/LH-RH;Synthetic gonadoliberin;Synthetic luteinizinghormone-releasing factor;Synthetic luteinizing hormone-releasing hormone;[(Pyro)Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2]; |
EINECS: | 251-553-1 |
Density: | 1.54 g/cm3 |
Appearance: | COA |
PSA: | 472.13000 |
LogP: | 1.10740 |
The Luteinizinghormone-releasing factor (swine), with the CAS registry number 33515-09-2, is also known as Synthetic gonadotropin-releasing hormone. It belongs to the product categories of Gonadotropin-Releasing Hormone(GnRH); Peptide Receptors; Peptide. Its EINECS registry number is 232-895-0. This chemical's molecular formula is C55H75N17O13 and molecular weight is 1182.29. What's more, its IUPAC name is called N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[(2-Amino-2-oxoethyl)carbamoyl] pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. It is a tropic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. And it is synthesized and released from neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family.
Physical properties about Luteinizinghormone-releasing factor (swine) are: (1)ACD/LogP: -2.03; (2)# of Rule of 5 Violations: 3; (3)ACD/LogD (pH 5.5): -5.07; (4)ACD/LogD (pH 7.4): -4.1; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 30; (10)#H bond donors: 19; (11)#Freely Rotating Bonds: 33; (12)Polar Surface Area: 283.46 Å2; (13)Index of Refraction: 1.713; (14)Molar Refractivity: 300.85 cm3; (15)Molar Volume: 767 cm3; (16)Surface Tension: 70.1 dyne/cm; (17)Density: 1.54 g/cm3.
You can still convert the following datas into molecular structure:
(1) SMILES: O=C(N)CNC(=O)[C@H]6N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)Cc2cncn2)Cc4c3ccccc3nc4)CO)Cc5ccc(O)cc5)CC(C)C)CCC/N=C(\N)N)CCC6
(2) InChI: InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
(3) InChIKey: XLXSAKCOAKORKW-AQJXLSMYSA-N