Reference

3-Alkylamino-

3-Alkylamino-.alpha.-aminomethyl-4-hydroxybenzyl alcohols with .beta.-adrenergic stimulant activity. Colella, Donald F.; Kaiser, Carl (Smithkline Corp., USA). U.S. US 3996383 7 Dec 1976, 4 pp. Division of U.S. 3,943,173. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-135. NCL: 424330000. APPLICATION: US 72-308867 22 Nov 1972. 3378-72-1 and 74-88-4 are just another two chemicals used in this study. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) I (R = Me, H; R1 = H, OEt) were treated with Me3CNHCH2Ph and the products were reduced by LiAlH4 and subjected to hydrogenolysis to give II (R = Me, H), which showed bronchodilator activity. .

Reactivity of a-halogenated imino compounds

Reactivity of a-halogenated imino compounds. Part XIV. Reaction of secondary N-1-(2-chloroalkylidene)amines with lithium tetrahydridoaluminate: synthesis and rearrangement of 1,2,2,-trisubstituted aziridines. De Kimpe, Norbert; Verhe, Roland; De Buyck, Laurent; Schamp, Niceas (Lab. Org. Chem., Fac. Agric. Sci., Ghent, Belg.). Recl. Trav. Chim.There are some reagents like 3378-72-1 is used in this study. Pays-Bas, 96(9), 242-6 (English) 1977. CODEN: RTCPA3. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) 1,2,2-Trisubstituted aziridines (e.g. I) were prepd. by redn. of secondary N-1-(2-chloroalkylidene)amines (e.g. Me2CClCH:NCHMe2) with LiAlH4. N-substituted 1-azaspiro[2.5]octanes were also synthesized by this method. Under appropriate gas chromatog. conditions, 1,2,2-trisubstituted aziridines underwent rearrangement to the corresponding secondary N-1-(alkylidene)amines (e. 3378-72-1 is the cas registry number. This chemical is also mentioned in this article.g. Me2CHCH:NCHMe2). The reaction mechanisms are discussed. ..