Detail of "3387-26-6"

Reference

Synthesis of cephalotaxine esters and correlation of their structures with antitumor activity

Synthesis of cephalotaxine esters and correlation of their structures with antitumor activity. Mikolajczak, Kenneth L.; Smith, Cecil R., Jr.; Weisleder, David (NRRC, ARS, Peoria, Ill., USA). J.Several reagents such as 3878-55-5 is used here. Med. Chem., 20(3), 328-32 (English) 1977. CODEN: JMCMAR. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 28 Of 22 esters of (-)-cephalotaxine [24316-19-6] prepd. and tested for antitumor activity against P388 lymphocytic leukemia in mice, the Me itaconate (I) [61568-74-9], Me fumarate (II) [61568-73-8], L-mandelate trichloroethyl carbonate (III) [61586-85-4], and trichloroethyl carbonate (IV) [61568-75-0] had consistent and significant activity. Of these compds., I and IV were most active. The enantiomer of I, (+)-cephalotaxine Me intaconate [61616-07-7], was inactive. Structure-activity relations are discussed. .

The molecular and crystal structure of 3,4-furandicarboxylic acid

The molecular and crystal structure of 3,4-furandicarboxylic acid. Semmingsen, Dag; Nordenson, Svein; Aasen, Agnar (Kjem. Inst., Univ. Oslo, Oslo N-0313, Norway). Acta Chem. Scand., Ser. A, A40(9), 559-65 (English) 1986. CODEN: ACAPCT. ISSN: 0302-4377. DOCUMENT TYPE: Journal CA Section: 75 (Crystallography and Liquid Crystals) Section cross-reference(s): 27 The structure of 3,4-furandicarboxylic acid was studied by Williams and Rundle (1964). The reported space group was P21/m, implying Cs symmetry of the mol. As a consequence, the 2 H bonds of lengths 2.56 (intra) and 2.There are some reagents like 3387-26-6 is used in this study.64 ? (inter) would be situated across special positions. The true space group of the material is P21/c at low temp. and at room temp. as well. The cell dimensions at 125 K were a 6.007(2), b 14.440(5), c 7.191(2) ?, and b 91.46(2), which implies a unit cell doubling along the c-axis repeat compared with the previous work. The present structural model gives a chem. consistent picture of the mols. with asym. H bonding in the crystal. The pseudosym. arrangement of mols. along H-bonded chains makes cooperative motions of the acidic protons possible. Thus, a pseudo-2-dimensional phase transition to P21/m between room temp. and the m.p. of the compd. (214°C) may take place. At. coordinates are given. .