Detail of "3407-93-0"

Reference

Hydrazinoacridine staining of proteins and glycoproteins in polyacrylamide gels

Hydrazinoacridine staining of proteins and glycoproteins in polyacrylamide gels. Carson, Steven D. (Dep.Several substances are used for example 3407-93-0 which is its cas registry number. Hum. Biol. Chem. Genet., Univ. Texas, Galveston, Tex., USA). Anal. Biochem., 78(2), 428-35 (English) 1977. CODEN: ANBCA2. DOCUMENT TYPE: Journal CA Section: 9 (Biochemical Methods) The histochem. method for staining polyaldehydes in tissue sections with p-hydrazinoacridine (I) was adapted for use in polyacrylamide gels. Whereas staining of histolog. prepns. was reportedly specific for polyaldehydes and independent of S2O52-, both glycoproteins (.beta. chain of haptoglobin) and nonglycoproteins (lysozyme and .alpha. chain of haptoglobin) were stained following IO4- oxidn., and satisfactory results were highly dependent on the presence of S2O52-. I staining of IO4--treated gels produced an extremely sensitive fluorescent labeling of the haptoglobin .beta.-chain and also stained haptoglobin .alpha. chain and lysozyme. The proteins could be visualized under visible light as yellow bands that were scanned spectrometrically at 440 nm. The .beta. chain of haptoglobin could be subjectively distinguished from the nonglycoproteins both by differential intensity of staining with (I) and Coomassie Brilliant Blue and by the yellow nature of the fluorescence. The sensitivity of I staining of the .beta. chain of haptoglobin compared favorably to that of the commonly used HIO4-Schiff staining procedures and provided the advantage that nonglycoproteins in complex mixts. could be localized in the gels. .

9-Hydrazinoacridine and 9-hydrazino-1,2,3,4-tetrahydroacridine derivatives: preparation and biological activity

9-Hydrazinoacridine and 9-hydrazino-1,2,3,4-tetrahydroacridine derivatives: preparation and biological activity. Pellerano, C. 3407-93-0 which is the cas registry number is also used here.; Savini, L. (Ist. Chim. Farm. Tossciol., Univ. Siena, Italy). Boll. Chim. Farm., 122(12), 582-8 (Italian) 1983. CODEN: BCFAAI. ISSN: 0006-6648. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 10 [(Arylmethylene)hydrazino]acridines I (R = Ph, halo- or methoxyphenyl, methoxynaphthyl, pyridyl) and tetrahydroacridines II [R1 = R, nitro-, (dialkylamino)-, or (methylenedioxy)phenyl, ethylcarbazolyl] were prepd.; and II exhibited bactericidal, protozoacidal, and virucidal activity. A mixt. of 9-hydrazinoacridine and PhCHO in EtOH was refluxed to give I (R = Ph). .