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CAS No.: | 3418-45-9 |
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Name: | 3-Quinolinol,1,2,3,4-tetrahydro- |
Article Data: | 8 |
Molecular Structure: | |
Formula: | C9H11 N O |
Molecular Weight: | 149.192 |
Synonyms: | 3-QUINOLINOL;3-Quinolinol, 1,2,3,4-tetrahydro- |
Density: | 1.154g/cm3 |
Melting Point: | 87 °C |
Boiling Point: | 318.686°C at 760 mmHg |
Flash Point: | 173.868°C |
PSA: | 32.26000 |
LogP: | 1.15350 |
Conditions | Yield |
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Stage #1: quinoline With borane-THF; boron trichloride In hexane at 0 - 65℃; for 4h; Inert atmosphere; Stage #2: With sodium perborate; water at 20℃; for 2h; Reagent/catalyst; Inert atmosphere; | A 70% B 21% |
Conditions | Yield |
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With ethanol; sodium at 80℃; for 2h; | 48% |
With ethanol; palladium at 55℃; Hydrogenation; | |
With potassium hydroxide; water elektrochemische Reduktion; | |
With sulfuric acid; water elektrochemische Reduktion; | |
With ethanol; sodium |
Conditions | Yield |
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Stage #1: quinoline With monochloroborane dimethyl sulfide complex In tetrahydrofuran at 0 - 65℃; for 48h; Inert atmosphere; Stage #2: With sodium perborate; water at 20℃; for 2h; Reagent/catalyst; Inert atmosphere; | 45% |
Multi-step reaction with 2 steps 1: tris(pentafluorophenyl)borate / chloroform-d1 / 24 h / 25 °C / Inert atmosphere 2: sodium perborate tetrahydrate / water; tetrahydrofuran / 1 h / 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: tris(pentafluorophenyl)borate / chloroform-d1 / 24 h / 85 °C / Inert atmosphere 2: sodium perborate tetrahydrate / water; tetrahydrofuran / 1 h / 20 °C / Inert atmosphere View Scheme |
3-hydroxyquinoline
sulfuric acid
water
1,2,3,4-tetrahydroquinolin-3-ol
Conditions | Yield |
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bei der elektrochemischen Reduktion an Blei-Kathoden; |
Conditions | Yield |
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bei der elektrochemischen Reduktion an Nickel-Kathoden; |
1,2,3,4-tetrahydroquinolin-3-ol
Conditions | Yield |
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With sodium perborate tetrahydrate In tetrahydrofuran; water at 20℃; for 1h; Inert atmosphere; |
1,2,3,4-tetrahydroquinolin-3-ol
tert-butyldimethylsilyl chloride
Conditions | Yield |
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With 1H-imidazole In tetrahydrofuran at 80℃; for 12h; | 38% |
Conditions | Yield |
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With triethylamine In tetrahydrofuran at 25℃; for 12h; | 18.4% |
1,2,3,4-tetrahydroquinolin-3-ol
Conditions | Yield |
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Multi-step reaction with 2 steps 1: 1H-imidazole / tetrahydrofuran / 12 h / 80 °C 2: ruphos; dichloro[1,3-bis(2,6-di-3-pentylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) / 1,4-dioxane / 16 h / 120 °C / Inert atmosphere View Scheme |
1,2,3,4-tetrahydroquinolin-3-ol
Conditions | Yield |
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Multi-step reaction with 3 steps 1: 1H-imidazole / tetrahydrofuran / 12 h / 80 °C 2: ruphos; dichloro[1,3-bis(2,6-di-3-pentylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) / 1,4-dioxane / 16 h / 120 °C / Inert atmosphere 3: N-Bromosuccinimide / dichloromethane / 2 h / 20 °C View Scheme |