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| CAS No.: | 343-94-2 |
|---|---|
| Name: | TRYPTAMINE HYDROCHLORIDE |
| Article Data: | 12 |
| Molecular Structure: | |
|
|
|
| Formula: | C10H12 N2 . Cl H |
| Molecular Weight: | 196.68 |
| Synonyms: | 1H-Indole-3-ethanamine,monohydrochloride (9CI); Indole, 3-(2-aminoethyl)-, monohydrochloride (8CI);2-(3-Indolyl)ethylamine hydrochloride; 3-(2-Aminoethyl)-1H-indolemonohydrochloride; 3-(2-Aminoethyl)indole hydrochloride; Tryptaminehydrochloride; Tryptamine monohydrochloride |
| EINECS: | 206-446-4 |
| Density: | 1.157g/cm3 |
| Melting Point: |
253-255 °C(lit.) |
| Boiling Point: | 378.8°Cat760mmHg |
| Flash Point: | 187.7°C |
| Appearance: | beige to light orange powder |
| Hazard Symbols: |
|
| Risk Codes: | 36/37/38-20/21/22 |
| Safety: | Poison by intravenous and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits very toxic NOx and HCl. |
| PSA: | 41.81000 |
| LogP: | 3.17140 |
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Chemistry
Chemistry informtion about 3-(2-Aminoethyl)Indole Hydrochloride (CAS NO.343-94-2) is:
IUPAC Name: 2-(1h-Indol-3-Yl)Ethanamine Hydrochloride
Synonyms: Tryptamine Hcl ; Tryptamine Hydrochloride ; Timtec-Bb Sbb000359 ; 3-(2-Aminoethyl)Indole Hcl ; 3-(2-Aminoethyl)Indole Hydrochloride ; 2-(3-Indolyl)Ethylamine Hydrochloride ; 1h-Indole-3-Ethanamine,Monohydrochloride ; 3-(2-Aminoethyl)-Indolmonohydrochloride
Product Categories: Tryptamines ; Indole ; Heterocyclic Compounds ; Indoles
MF: C10H13ClN2
MW: 196.68
EINECS: 206-446-4
Melting Point: 253-255 °C(lit.)
Flash Point: 187.7 °C
Boiling Point: 378.8 °C at 760 mmHg
Vapour Pressure: 6.14E-06 mmHg at 25°C
Enthalpy of Vaporization: 62.67 kJ/mol
Merck: 14,9796
BRN: 3568419
Following is the molecular structure of 3-(2-Aminoethyl)Indole Hydrochloride (CAS NO.343-94-2) is:
Toxicity Data With Reference
| 1. | scu-rat LDLo:1300 mg/kg | JPMRAB Japanese Journal of Medical Sciences, Part IV: Pharmacology. 2 (1927),77. | ||
| 2. | ipr-mus LD50:197 mg/kg | YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. 94 (1974),1620. | ||
| 3. | scu-mus LD50:504 mg/kg | RPTOAN Russian Pharmacology and Toxicology. Translation of FATOAO. 33 (1970),180. | ||
| 4. | ivn-mus LD50:109 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 23 (1964),43. | ||
| 5. | scu-rbt LDLo:1000 mg/kg | JPMRAB Japanese Journal of Medical Sciences, Part IV: Pharmacology. 2 (1927),77. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Poison by intravenous and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits very toxic NOx and HCl.
Hazard Codes:
Xn
Xi
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R41:Risk of serious damage to the eyes.
R37/38:Irritating to respiratory system and skin.
R22:Harmful if swallowed.
Safety Statements:
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S36:Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: NL4375000
F:
F 3: Hygroscopic.
F 8: Photosensitive.
F 10: Keep under argon.
Specification
3-(2-Aminoethyl)Indole Hydrochloride (CAS NO.343-94-2) is a beige to light orange powder.
First Aid Measures:
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Handling and Storage:
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Store in a tightly closed container.