Detail of "34493-98-6"

Reference

Antibiotic metabolism and administration methods for infants

Antibiotic metabolism and administration methods for infants. Nakazawa, Susumu; Sato, Hajime; Fujii, Hisamichi; Kojima, Sadasuke; Niino, Kenji; Hirama, Yuichi; Narita, Akira; Tanaka, Hide; Irino, Taiichi (Ebara Hosp., Tokyo, Japan). Tokyo-to Eisei-Kyoku Rinsho Kenkyu Kiyo, Volume Date 1976 323-9 (Japanese) 1977. CODEN: TERKDH. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Cefazolin (I) [25953-19-9] or T-1220 [59703-84-3] injected i.v. at 50 mg/kg into infants remained in the blood at a relatively high concn. for a prolonged time. 3',4'-Dideoxykanamycin B [34493-98-6] (2 mg/kg, i.m.) remained in the blood for 12 h at an effective concn. which was higher than the concn. found in older children who had been similarly injected. The optimum condition for the administration of I was 25-50 mg/kg, i.m. or i.v., and those of T-1220 and 3',4'-dideoxykanamycin were 50-100 mg/kg, i.v., and 2-4 mg/kg, i.m., resp.

Serratia marcescens sensitivity to antibiotics

Serratia marcescens sensitivity to antibiotics. Senen Alvarez, J.; Garcia Riestra, C. (Dep. Microbiol., Univ. Santiago, Santiago de Compostela, Spain). Acta Cient. Compostelana, 14(4), 507-14 (Spanish) 1977. CODEN: ACCCAW. ISSN: 0567-7378. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Of the 152 clin. isolates of S. marcescens tested, 143 were inhibited by amikacin [37517-28-5] at ￡20 mg/mL. Sensitivity to sisomicin [32385-11-8] was similar. Only 61 of the strains were inhibited by ￡6.25 mg tobramycin [32986-56-4]/mL and 13 were resistant to the antibiotic (minimal inhibitory concns. >25 mg/mL). Resistance to gentamicin [1403-66-3] was obsd. in 38 strains and resistance to dibekacin [34493-98-6] in 115. Only 41 and 26 of the isolates were inhibited by kanamycin [8063-07-8] and streptomycin [57-92-1], resp., at ￡26 mg/mL.