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CAS No.: | 3458-22-8 |
---|---|
Name: | Improsulfan hydrochloride |
Molecular Structure: | |
Formula: | C8H19 N O6 S2 . Cl H |
Molecular Weight: | 325.86 |
Synonyms: | 3,3'-iminodi-1- propanol dimethanesulfonate;864 T;alkylating agent 864;bis(3-mesyloxypropyl)amine;dimesyloxydipropylamine tosylate;improsan;improsan hydrochloride;improsan tosylate;NSC-102627;NSC-140117;yoshi 864 |
Density: | g/cm3 |
Melting Point: | 94-95° |
Boiling Point: | 510.1°Cat760mmHg |
Flash Point: | 262.3°C |
Safety: | Poison by intraperitoneal and intravenous routes. Human systemic effects by intravenous route: somnolence, hypermotility, diarrhea, nausea or vomiting. Questionable carcinogen with experimental neoplastigenic data. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. |
PSA: | 115.53000 |
LogP: | 2.66310 |
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Molecular Formula of Yoshi 864 (CAS NO.3458-22-8): C8H20ClNO6S2
Molecular Weight: 325.8305 g/mol
Structure of Yoshi 864 (CAS NO.3458-22-8):
IUPAC Name: 3-(3-Methylsulfonyloxypropylamino)propyl methanesulfonate hydrochloride
1. | oms-hmn:lym 100 mg/L | EJCAAH European Journal of Cancer. 14 (1978),741. | ||
2. | ipr-rat TDLo:3744 mg/kg/52W-I:NEO | NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-18 ,1978. | ||
3. | ivn-hmn TDLo:5400 µg/kg/2D-I:CNS,GIT | CANCAR Cancer. 35 (1975),1145. | ||
4. | ivn-rat LD50:75 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1139. | ||
5. | ipr-mus LD10:170 mg/kg | JMCMAR Journal of Medicinal Chemistry. 20 (1977),515. |
NCI Carcinogenesis Bioassay (ipr); Clear Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-18 ,1978. .
Poison by intraperitoneal and intravenous routes. Human systemic effects by intravenous route: somnolence, hypermotility, diarrhea, nausea or vomiting. Questionable carcinogen with experimental neoplastigenic data. Human mutation data reported. When heated to decomposition Yoshi 864 (CAS NO.3458-22-8) emits very toxic fumes of NOx, SOx, and HCl.
Yoshi 864 ,its cas register number is 3458-22-8. It also can be called 1-Propanol, 3,3'-iminodi-, dimethanesulfonate (ester),
hydrochloride ; and Improsulfan hydrochloride .