Detail of > 3458-98-8
- CAS Number:
- 3458-98-8
- Name:
Phenol, 3-(2-aminoethyl)-, hydrochloride
- Formula:
- C8H12ClNO
- Molecular Structure:

- Synonyms:
- 3-(2-Aminoethyl)phenolhydrochloride;3-Hydroxyphenethylamine hydrochloride;m-Tyramine hydrochloride;2-(3-Hydroxyphenyl)ethanamine hydrochloride;2-(3-Hydroxyphenyl)ethylamine hydrochloride;Phenol, m-(2-aminoethyl)-,hydrochloride (8CI);Phenol,3-(2-aminoethyl)-, hydrochloride (9CI);
- Molecular Weight:
- 173.64
- EINECS:
- 222-396-6
- Boiling Point:
- 275.5 °C at 760 mmHg
- Flash Point:
- 120.4 °C
- Solubility:
- H2O:≥10 mg/mL
- Appearance:
- off-white to tan solid
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38
- Safety:
- 26-36Details
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Reference
- Effects of some phenylalkylamines on Heobania vermiculata nerve cells
- Effects of some phenylalkylamines on Heobania vermiculata nerve cells. Avoli, M.; Barra, P. F. A.; Brancati, A.; Eusebi, F.; Roseghini, M. (Dep. Hum. Physiol. Med. Pharmacol., Univ. Rome, Rome, Italy). Comp. Biochem. Physiol. C, 59C(2), 173-5 (English) 1978. CODEN: CBPCBB. ISSN: 0306-4492. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) M- [3458-98-8] and p-tyramine-HCl [60-19-5], hordenine sulfate (I sulfate) [622-64-0], leptodactyline picrate [66967-84-8], candicine iodide [1976-98-3], as well as acetylcholine [51-84-3] and dopamine [51-61-6] (all at 0.2M) affected the firing pattern of most of the nerve cells of the periesophageal ganglionic ring of H. vermiculata tested on perfusion and ionophoretic application. The action of I and candicine was similar to that of acetylcholine in hyperpolarized and depolarized cells. The presence of a COOH-group in the tyramine mol. (m- [587-33-7] and p-tyrosine [60-18-4]) eliminated dopamine-like activity. The conversion of the quaternary N of the candicine mol. into a tertiary N (I) eliminated cholinomimetic activity.
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