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CAS No.: | 3544-94-3 |
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Name: | Chloramphenicol hemisuccinate |
Article Data: | 8 |
Molecular Structure: | |
Formula: | C15H16 Cl2 N2 O8 |
Molecular Weight: | 423.207 |
Synonyms: | Butanedioicacid, mono[2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester,[R-(R*,R*)]-; Succinic acid, ester with chloramphenicol (6CI); Succinic acid, a-monoester withD-threo-(-)-2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]acetamide(8CI); Acetamide, 2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]-,a-(hydrogen succinate),D-(-)-threo- (8CI); Chloramphenicol 3-monosuccinate; Chloramphenicol acidsuccinate; Chloramphenicol hemisuccinate; Chloramphenicol hydrogen succinate;Chloramphenicol monosuccinate; Chloramphenicol succinate; Chloromycetinsuccinate; Chronicin foam; Kemicetine succinate; Levomycetin hemisuccinate;Levomycetin succinate; Paraxin succinate |
EINECS: | 222-590-0 |
Density: | 1.536g/cm3 |
Melting Point: | 127 °C |
Boiling Point: | 716.3°Cat760mmHg |
Flash Point: | 387°C |
Safety: | Moderately toxic by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl− and NOx. See also other chloramphenicol entries. |
PSA: | 162.24000 |
LogP: | 2.68820 |
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IUPAC Name: 4-[2-[(2,2-Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoic acid
Synonyms of Chloramphenicol succinate (CAS NO.3544-94-3) : (2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl) hydrogen (R-(R*,R*))-succinate ; Chloramphenicol acid succinate ; Chloramphenicol hydrogen succinate ; Chloramphenicol monosuccinate
CAS NO:3544-94-3
Molecular Formula:C15H16Cl2N2O8
Molecular Weight :423.2021
Molecular Structure :
EINECS: 222-590-0
Index of Refraction: 1.589
Surface Tension: 65.7 dyne/cm
Density: 1.536 g/cm3
Flash Point: 387 °C
Enthalpy of Vaporization: 109.91 kJ/mol
Boiling Point: 716.3 °C at 760 mmHg
Vapour Pressure: 1.56E-21 mmHg at 25°C
Chloramphenicol succinate (CAS NO.3544-94-3) is used as intermediate in organic synthesis.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
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guinea pig | LD50 | intravenous | 1gm/kg (1000mg/kg) | Farmaco, Edizione Scientifica. Vol. 9, Pg. 21, 1954. | |
mouse | LD50 | intraperitoneal | 1400mg/kg (1400mg/kg) | Farmaco, Edizione Scientifica. Vol. 9, Pg. 21, 1954. | |
mouse | LD50 | intravenous | 1500mg/kg (1500mg/kg) | Farmaco, Edizione Scientifica. Vol. 9, Pg. 21, 1954. | |
mouse | LD50 | oral | 11gm/kg (11000mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 135, 1970. | |
mouse | LD50 | subcutaneous | 4200mg/kg (4200mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 135, 1970. | |
rat | LD50 | intravenous | 1720mg/kg (1720mg/kg) | Therapie. Vol. 22, Pg. 1405, 1967. | |
rat | LD50 | oral | 8300mg/kg (8300mg/kg) | Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 135, 1970. | |
rat | LD50 | subcutaneous | 2400mg/kg (2400mg/kg) | Therapie. Vol. 22, Pg. 1405, 1967. |
EPA Genetic Toxicology Program.
Moderately toxic by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When Chloramphenicol succinate (CAS NO.3544-94-3) is heated to decomposition, it emits toxic fumes of Cl− and NOx. See also other chloramphenicol entries.