CAS No.35661-39-3,FMOC-Ala-OH Suppliers,MSDS download

Products Categories

Pharmaceutical (141)
Others (69)
Organic Chemicals (44)
Reagent (8)
Food Additives (2)
Basic Inorganic Chemicals (2)
Materials (1)
Plant Extract (1)

Basic Information

Molecular Structure:
CAS No.:	35661-39-3
Name:	FMOC-Ala-OH
Article Data:	48

Formula:	C₁₈H₁₇NO₄
Molecular Weight:	311.337
Synonyms:	(2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propanoicacid;(9-Fluorenylmethoxycarbonyl)-L-alanine;(S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propionic acid;(S)-N-Fmoc-alanine;FMOC-Alanine;N-(9-Fluorenylmethoxycarbonyl)alanine;N-9-Fluorenylmethoxycarbonyl-L-alanine;NPC 14688;NSC 334296;Fmoc-Ala-OH;Fmoc-β-Ala-OH;
EINECS:	252-660-6
Density:	282 g/cm³
Melting Point:	147-153 °C(lit.)
Boiling Point:	544.1 °C at 760 mmHg
Flash Point:	282.9 °C
Solubility:	Soluble in water.
Appearance:	white to light yellow crystal powder
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	24/25-36/37/39-27-26
PSA:	79.12000
LogP:	3.20260

Synthetic route

: C32H27NO5

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With potassium phosphate; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; ascorbic acid In water; acetonitrile at 20℃; for 1h; Irradiation;	100%

: 56-41-7
L-alanin

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane; water at 20℃; for 18h;	99%
With sodium carbonate In N,N-dimethyl-formamide for 0.166667h; Ambient temperature;	96%
With sodium carbonate In 1,4-dioxane; water at 20℃; for 18h;

: 56-41-7
L-alanin

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
In water at 110℃; for 0.0833333h; Microwave irradiation; Green chemistry; chemoselective reaction;	96%
In ethanol; water at 60℃; for 4h; chemoselective reaction;	86%

: 56-41-7
L-alanin

polymer-bound Fmoc-O-succinimide: polymer-bound Fmoc-O-succinimide

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With potassium carbonate In acetone at 20℃; for 24h;	95%

: 56-41-7
L-alanin

: 1370440-36-0
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-oxo-2-(piperidin-1-yl)acetimidoyl cyanide

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone	93.2%

: 56-41-7
L-alanin

: 88744-04-1
(9-fluorenyl)methyl pentafluorophenyl carbonate

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone Ambient temperature;	93%

: 56-41-7
L-alanin

: 1370440-32-6
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-(ethylamino)-2-oxoacetimidoyl cyanide

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone	92.6%

: 56-41-7
L-alanin

: 99503-04-5
Carbonic acid 3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-8-en-4-yl ester 9H-fluoren-9-ylmethyl ester

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With tertiary amine In 1,4-dioxane; water for 3h;	91%

: 56-41-7
L-alanin

: Carbonic acid 1,3-dioxo-1,3-dihydro-isoindol-2-yl ester 9H-fluoren-9-ylmethyl ester

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 20℃; for 2h;	91%

ether-petroleum ether: ether-petroleum ether

: 56-41-7
L-alanin

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 35661-39-3
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Conditions

Conditions	Yield
In 1,4-dioxane; sodium carbonate	90.2%

...Expand

Total:204 Page 1 of 6 1 2 3 4 5 6 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 35661-39-3

Standards and Recommendations

APPEARANCE OF FMOC-l-ALANINE: White to off-white crystalline powder
ASSAY OF FMOC-L-AL: 99.0% min
OPTICAL ROTATION [a]20: -17.5 ° ~ -29.5°(C=1 in DMF)
SOLUTION CLARITY: clear
Fe: 10ppm max
HEAVY METALS 10ppm max
As: 2ppm max
LOSS ON DRYING: 0.5% max

Specification

The Fmoc-L-alpha-Alanine, with the CAS registry number 35661-39-3, is also known as NSC334296. It belongs to the product categories of Protected Amino Acids; Fluorenes, Flurenones; Amino Acids; Alanine [Ala, A]; Fmoc-Amino Acids and Derivatives; Amino Acids (N-Protected); Biochemistry; Fmoc-Amino Acids; Fmoc-Amino Acid Series. Its EINECS registry number is 252-660-6. This chemical's molecular formula is C₁₈H₁₇NO₄ and molecular weight is 311.33188. Its IUPAC name is called 2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. The product should be sealed and stored in cool and dry place.

Physical properties of Fmoc-L-alpha-Alanine: (1)ACD/LogP: 3.54; (2)ACD/LogD (pH 5.5): 1.52; (3)ACD/LogD (pH 7.4): 0.02; (4)ACD/BCF (pH 5.5): 2.78; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 19.31; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 5; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 5; (11)Index of Refraction: 1.607; (12)Molar Refractivity: 83.91 cm³; (13)Molar Volume: 242.7 cm³; (14)Surface Tension: 55.3 dyne/cm; (15)Density: 1.282 g/cm³; (16)Flash Point: 282.9 °C; (17)Enthalpy of Vaporization: 86.58 kJ/mol; (18)Boiling Point: 544.1 °C at 760 mmHg; (19)Vapour Pressure: 1.13E-12 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
(2)InChI: InChI=1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)
(3)InChIKey: QWXZOFZKSQXPDC-UHFFFAOYSA-N