Detail of "3571-88-8"

CAS Number:
3571-88-8
Name:
Thiazolium,2,2'-[3-[2-(3-heptyl-4-methyl-2(3H)-thiazolylidene)ethylidene]-1-propene-1,3-diyl]bis[3-heptyl-4-methyl-,iodide (1:2)
Molecular Structure:
Formula:
C38H61 N3 S3 . 2 I
Molecular Weight:
909.91498
Synonyms:
Thiazolium,2,2'-[3-[(3-heptyl-4-methyl-2(3H)-thiazolylidene)ethylidene]-1-propene-1,3-diyl]bis[3-heptyl-4-methyl-,diiodide (9CI); Thiazolium,2,2'-[3-[2-(3-heptyl-4-methyl-4-thiazolin-2-ylidene)ethylidene]propenylene]bis[3-heptyl-4-methyl-,diiodide (8CI); 2,2'-Pentamethinethiazolocyanine 3,3''-diiodide,4,4',4''-trimethyl-3,3',3''-triheptyl-8-(2''-thiazolyl)-;4,4'-Dimethyl-3,3'-di-n-heptyl-8-[2-(4-methyl-3-n-heptylthiazole)]2,2'-dicarbocyanindiiodide;4,4'-Dimethyl-3,3'-dihepthyl-8-[2-(4-methyl-3-heptylthiazole)]-2,2'-dicarbocyaninediiodide;4,4'-Dimethyl-3,3'-diheptyl-8-[2-(4-methyl-3-heptylthiazole)]-2,2'-dicarbocyaninediiodide; Kankohso 101; NK 19; Photosensitizer 101; Platonin J; Platonindiiodide; Platonin iodide
EINECS:
222-681-5
Density:
g/cm³
Boiling Point:
°Cat760mmHg
Flash Point:
°C

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Toxicity of NK19, a photosensitizing dye: Toxicity of NK19, a photosensitizing dye. Toxicity in mice and rats. Kimoto, Tetsuo; Nishitani, Kozo (Dep. Exp. Pathol., Kawasaki Med. Coll., Okayama, Japan). Kanko Shikiso, 85, 43-50 (Japanese) 1976. CODEN: KASHAJ. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The LD50 values of NK 19 (I) [3571-88-8] were 46.9 and 50.5 mg/kg, resp., for male and female mice via the i.p. route. The values were 1539 and 1571 mg/kg, resp., for male and female rats after oral administration. Poisoning symptoms included hair bristling, short breathing, convulsion, liver and kidney parenchymatous degeneration and others. In subacute and chronic expts., I (at 1 and 5 mg/kg for 5 weeks or at 0.2, 1, and 5 mg/kg for 15 weeks) administered i.p. to rats did not cause changes in the body wt., food consumption, and pathohistol. parameters.

Effect of cyanine and aminovinyl dyes on the peritoneal mast cells of rats: Effect of cyanine and aminovinyl dyes on the peritoneal mast cells of rats. Sugiyama, Katsumi; Utsumi, Kozo (Med. Sch., Okayama Univ., Okayama, Japan). Kanko Shikiso, 85, 36-42 (Japanese) 1976. CODEN: KASHAJ. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The effect of cyanine and aminovinyl dyes on the compd. 48/80-induced degranulation and histamine [51-45-6] release by isolated rat mast cells was studied. Of 12 cyanine dyes tested, NK 76 (I; n = 1) [905-97-5], NK 136 (I; n = 2) [514-73-8], NK 19 (II; R = C7H15) [3571-88-8], NK 2251 [53213-94-8], NK 266 [37187-89-6], and NK 2252 [62008-59-7] inhibited the compd. 48/80-induced degranulation, whereas NK 88 (I; n = 0) [2197-01-5], NK 2 (II; R = Me) [37187-85-2], NK 2011 [62008-57-5], NK 1160 [62008-58-6], NK 1529 [62008-60-0] and NK 4 [4846-34-8] had no effect. All aminovinyl dyes (NK 343 [1463-95-2] and NK 355 [21034-17-3]) tested were without effect. NK 2251 also inhibited compd. 48/80- or ATP [56-65-5]-induced histamine release but had no effect on ATP-induced cell swelling. The mechanism of histamine release is discussed.