Detail of "3572-87-0"

CAS Number:
3572-87-0
Name:
2(1H)-Pyrimidinone,5,6-dihydro-4,6-bis(methoxyamino)-
Molecular Structure:
Formula:
C6H12 N4 O3
Molecular Weight:
188.1845
Synonyms:
4,6-Dimethoxyamino-2-oxo-1,2,5,6-tetrahydropyrimidine;N-4-Methoxy-6-methoxyamino-5,6-dihydrocytosine
Density:
1.46g/cm³
Boiling Point:
°Cat760mmHg
Flash Point:
°C

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Mutagenic action of O-methylhydroxylamine on transforming DNA: Mutagenic action of O-methylhydroxylamine on transforming DNA. Bresler, S. E.; Machkovskii, V. V.; Perumov, D. A.; Budovskii, E. I. (B. P. Konstantinov Inst. Nucl. Phys., Leningrad, USSR). Genetika (Moscow), 19(9), 1397-403 (Russian) 1983. CODEN: GNKAA5. ISSN: 0016-6758. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Section cross-reference(s): 3 Exposure of transforming DNA of Bacillus subtilis to 1 M H2NOMe [67-62-9] at pH 4.5-6 and 6 (50°) caused increased mutation frequency (4-5-fold). The initial rate of accumulation at pH 4.5 was 5-8-fold higher than that at pH 6. Possible mechanisms of actions are discussed in terms of H2NOMe interaction with cytosine [71-30-7], N4-methoxycytosine [20555-89-9], and N4-methoxy-6-methoxyamino-5,6-dihydrocytosine [3572-87-0].