CAS No.3598-37-6,Acepromazine maleate Suppliers,MSDS download

Products Categories

Pharmaceutical (64)
Others (16)
Organic Chemicals (15)
Reagent (4)
Materials (2)
Food Additives (1)

Basic Information

Molecular Structure:
CAS No.:	3598-37-6
Name:	Acepromazine maleate

Formula:	C₁₉H₂₂N₂OS•C₄H₄O₄
Molecular Weight:	442.53
Synonyms:	10-(3-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone maleate (1:1);A 23051;Phenothiazine, 2-acetyl-10-(3-(dimethylamino)propyl)-, maleate;Plegicil;Soprontin;
EINECS:	222-748-9
Density:	1.155g/cm3
Melting Point:	135-136 °C
Boiling Point:	497oC at 760 mmHg
Flash Point:	254.4oC
Appearance:	Yellow crystalline solid
Hazard Symbols:	Xn,N
Risk Codes:	22-50/53
Safety:	60-61
PSA:	123.45000
LogP:	4.22040

Total:88 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 3598-37-6

Specification

Acepromazine maleate(CAS NO.3598-37-6) is also called Atavet; Calmivet; 1-[[10-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone; 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)-ethanon(z)-2-bute; 1-[10-[3-Dimethylamino)propyl]-10H-phenothiazin-2-yl]-ethanon(z)-2-butened; 10-(3-(Dimethylamino)propyl)phenothiazin-2-ylmethylketonemaleate(1:1); 2-Acetyl-10-(3-(dimethylamino)propyl)phenothiazine, maleate. Acepromazine maleate is high toxic. It is flammable. It will produce toxic nitrogen oxides and sodium oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry. It is used as an antipsychotic in humans, but frequently in animals as a sedative and antiemetic.

Physical properties about Acepromazine maleate are: (1)ACD/LogP: 4.08; (2)ACD/LogD (pH 5.5): 1.05; (3)ACD/LogD (pH 7.4): 2.13; (4)ACD/BCF (pH 5.5): 1.00 ; (5)ACD/BCF (pH 7.4): 8.34; (6)ACD/KOC (pH 5.5): 3.66; (7)ACD/KOC (pH 7.4): 44.33; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 5; (10)Flash Point: 254.4 °C; (11)Enthalpy of Vaporization: 76.49 kJ/mol; (12)Boiling Point: 497 °C at 760 mmHg; (13)Vapour Pressure: 5.13E-10 mmHg at 25°C

You can still convert the following datas into molecular structure:
(1)InChI=1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19;5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+;
(2)InChIKey=FQRHOOHLUYHMGG-WLHGVMLRSA-N;
(3)SmilesCC(=O)c1ccc2c(c1)N(c3ccccc3S2)CCCN(C)C.C(=C/C(=O)O)\C(=O)O

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	6250ug/kg (6.25mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP	American Journal of Emergency Medicine. Vol. 11, Pg. 247, 1993.
mouse	LD50	intravenous	65mg/kg (65mg/kg)		Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 87, 1962.
mouse	LD50	subcutaneous	175mg/kg (175mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 113, Pg. 53, 1957.
mouse	LDLo	oral	270mg/kg (270mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 113, Pg. 53, 1957.
rat	LD50	intravenous	95mg/kg (95mg/kg)		"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 6, 1989.
rat	LD50	oral	400mg/kg (400mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 123, Pg. 78, 1959.
women	LDLo	oral	496mg/kg (496mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Journal of Analytical Toxicology. Vol. 22, Pg. 166, 1998.