Reference

Influence of cytochalasins on sugar and amino acid absorption in the mouse

Influence of cytochalasins on sugar and amino acid absorption in the mouse. Glinsukon, T.; Toskulkao, C.; Wangpanish, W.; Chulasamaya, M. (Fac. Sci., Mahidol Univ.There are some reagents with their cas registry numbers 63-91-2 and 14930-96-2 are used in this study., Bangkok, Thailand). Toxicon, Suppl. 3, 173-6 (English) 1983. CODEN: TOXIA6. ISSN: 0041-0101. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Cytochalasin B [14930-96-2] and cytochalasin E [36011-19-5] (10 mg/mL) increased slightly the final concn. of maltose [69-79-4] in mucosal solns. of mouse jejunum and this led to a decrease in maltose digestion, but these differences were not significant. Similarly, both cytochalasins did not significantly reduce sucrose [57-50-1] digestion but it seemed to be slightly stimulated. The cytochalasins inhibited the intestinal absorption of glucose [50-99-7] derived from maltose and sucrose, and stimulated the absorption of fructose [57-48-7] derived from sucrose. They also inhibited the active transport of galactose [59-23-4] and L-phenylalanine [63-91-2]. Apparently, cytochalasins inhibited Na+-dependent active transport of glucose, galactose, and phenylalanine, but they seem to stimulate carrier-mediated transport of fructose and passive transport of mannose [3458-28-4] and xylose [58-86-6]. .

Cytochalasin E: production by strains of Aspergillus clavatus and toxic effects upon the embryonic chick

Cytochalasin E: production by strains of Aspergillus clavatus and toxic effects upon the embryonic chick. Vesela, Doubravka; Vesely, D.; Jelinek, R. (Inst. Exp. Med., Czech. Acad. Sci., Prague 517 83, Czech.). Microbiol., Aliments, Nutr., 1(4), 393-8 (English) 1983. CODEN: MANUEP. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Among 16 strains of A. clavatus isolated from wheat and barley, 7 produced 30-80 mg, 4 strains 200-500 mg, and 1 strain 700 mg cytochalasin E (I) [36011-19-5]/kg wheat. The total amt. of I was directly assocd. with the amt. of damaged grain incapable of sprouting. The direct embryotoxicity of I estd. on 2, 3 and 4-day old chick embryos was approx. equal to that of aflatoxin G1 (ED50 for day 2 = 0.016 mg, day 3 = 0.050 mg, and day 4 = 0.180 mg). The high toxicity of I combined with the productivity of A. clavatus represents a considerable danger in cases of these fungal strains infesting raw foodstuffs and feeds.