Detail of "36286-75-6"

Reference

3-Aryl-as-triazines as potential antiinflammatory agents

3-Aryl-as-triazines as potential antiinflammatory agents. O'Rourke, M.; Lang, S. A., Jr.; Cohen, E. (Lederle Lab. Div., Am. Cyanamid Co., Pearl River, N. Y., USA). J. Med. Chem., 20(5), 723-6 (English) 1977. CODEN: JMCMAR. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 28 Of 14 title compds. 62230-51-7 and 36286-75-6 are also in the experiment. (I:R1 = 2-pyridyl, Ph, substituted Ph; R2, R3 = H, Me, Ph) prepd. by the condensation of .alpha.,.beta.-dicarbonyl compds. with aryl amidrazones, only 3-(p-chlorophenyl)-as-triazine [57446-73-8] and 3-(p-fluorophenyl)-as-triazine [62230-41-5] were active against carrageenan-induced edema in rats : the compds. were inactive against adjuvant-induced arthritis in rats. .