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CAS No.: | 36304-84-4 |
---|---|
Name: | Dimemorfan phosphate |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C18H25N.H3O4P |
Molecular Weight: | 353.398 |
Synonyms: | DIMEMORFAN PHOSPHATE;(9alpha,13alpha,14alpha)-3,17-dimethylmorphinan dihydrogen phosphate;Astomin;dimemorphan phosphate;Morphinan, 3,17-dimethyl-, (9α,13α,14α)-, phosphate (1:1) |
EINECS: | 252-958-6 |
Density: | 1.07g/cm3 |
Melting Point: | 267-269° |
Boiling Point: | 366.9°Cat760mmHg |
Flash Point: | 158.3°C |
Safety: | Poison by intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Used as an antitussive agent. When heated to decomposition it emits very toxic fumes of NOx and POx. See also PHOSPHATES. |
PSA: | 90.81000 |
LogP: | 2.69250 |
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D-3-methyl-N-methylmorphinan phosphate(36304-84-4) exists as bitter-tasting crystals. D-3-methyl-N-methylmorphinan phosphate(36304-84-4) is slightly soluble in H2O and methanol, and it is insoluble in acetone, ethanol, ether.
Molecular Formula: C18H25N.H3O4P.
Molecular Weight: 353.44.
Density: 1.07g/cm3.
Boiling Point: 366.9 ℃ at 760mmHg.
Flash Point: 158.3 ℃.
Molecular Structure:
1. | orl-rat LD50:690 mg/kg | MEIEDD Merck Index. 10 (1983),466. | ||
2. | ipr-rat LD50:124 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 6 (1972),1207. | ||
3. | scu-rat LD50:556 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),345. | ||
4. | ivn-rat LD50:57 mg/kg | MEIEDD Merck Index. 10 (1983),466. | ||
5. | orl-mus LD50:475 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 26 (1976),353. | ||
6. | scu-mus LD50:223 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 26 (1976),353. | ||
7. | ivn-mus LD50:33,900 µg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 6 (1972),1207. | ||
8. | ivn-dog LD50:35 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 26 (1976),353. |