Reference

Method for preparation of aqueous doripenem solution

All Rights Reserved. Method for preparation of aqueous doripenem solution. Nakanishi, Hayao (Shionogi & Co., Ltd., Japan). PCT Int. Appl. WO 2006126630 A1 30 Nov 2006, 13pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IS, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (Japanese). (World Intellectual Property Organization). CODEN: PIXXD2. APPLICATION: WO 2006-JP310437 25 May 2006. PRIORITY: JP 2005-153704 26 May 2005. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Disclosed is a method for the prepn. of an aq. doripenem soln. while minimizing the thermal decompn. of doripenem. It is found that the thermal decompn. of doripenem can be prevented by heating an aq. doripenem suspension in a flow system, and thus an aq. doripenem soln. can be prepd.Except for chemicals metioned above, 364622-82-2 and 364622-81-1 are also used. .

Doripenem hydrate

All Rights Reserved. Doripenem hydrate. Kaneko, Akihiro (Japan). Shika Yakubutsu Ryoho, 25(1), 22-24 (Japanese) 2006 Nippon Shika Yakubutsu Ryoho Gakkai. CODEN: SYRYEJ. ISSN: 0288-1012. DOCUMENT TYPE: Journal; General Review CA Section: 1 (Pharmacology) Section cross-reference(s): 10 A review discussing the antibacterial spectrum, pharmacokinetics, and clin. 364622-82-2 which is the cas registry number of some chemical is mentioned. pharmacol. of doripenem hydrate. .