Reference

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones. Paget, Steven D.; Foleno, Barbara D.; Boggs, Christine M.; Goldschmidt, Raul M.; Hlasta, Dennis J.; Weidner-Wells, Michele A.; Werblood, Harvey M.; Wira, Ellyn; Bush, Karen; Macielag, Mark J. ( Johnson & Johnson Pharmaceutical Research & Development, Raritan, NJ 08869, USA). Bioorganic & Medicinal Chemistry Letters, 13(23), 4173-4177 (English) 2003 Elsevier Science B.Several substances with their cas registry numbers 643-79-8 and 369-34-6 may be metioned in this study.V. CODEN: BMCLE8. ISSN: 0960-894X. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 10 A novel series of oxazolidinones contg. a pyrroloaryl substituent, e.g., I, was synthesized and screened against a representative panel of susceptible and resistant Gram-pos. bacteria. Several members of this series were found to have antibacterial activity comparable to or better than linezolid. .