Detail of "3696-23-9"

Reference

Preparation of 2-aminobenzothiazoles

Preparation of 2-aminobenzothiazoles. Rentel, Heinz; Papenfuhs, Theodor (Hoechst A.-G. , Fed. Rep. Ger.). Ger. Offen. DE 3522941 A1 8 Jan 1987, 4 pp. (Germany) CODEN: GWXXBX. CLASS: ICM: C07D277-82. APPLICATION: DE 85-3522941 27 Jun 1985. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 45 The title compds. (I; R1, R2 = H, halo, C1-4 alkyl, C1-4 alkoxy, NO2) were prepd. 4-O2NC6H4NHCSNH2, NH4Br, and perlite were heated at 100-105° for 2.5-3 h in concd. H2SO4 to afford 91. 3696-23-9 and 6285-57-0 are just another two chemicals used in this study.0% I (R1 = H, R2 = 6-NO2). .

Preparation of thiazole derivatives and analogs for the treatment of disorders caused by free fatty acids

Eriksson, Bjoern; Kurz, Guido; Hedberg, Christian (Betagenon AB, Swed.). PCT Int. Appl. WO 2007010281 A2 25 Jan 2007, 99pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IS, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR.Chemicals with cas numbers 919365-06-3 and 3696-23-9 also play role. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: A61K. APPLICATION: WO 2006-GB2743 21 Jul 2006. PRIORITY: US 2005-595620P 21 Jul 2005; SE 2005-1721 21 Jul 2005; US 2006-744422P 7 Apr 2006. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 Title compds. I [X = (CR8R9)n; n = 0-3; T = S or O; Y = SO2, CO, :CR10; W = NR7, NR7CO, NR7SO2, etc.; one of A1 or A2 = a double bond and the other = a single bond; when A1 = a single bond, A2 = a double bond and R6 is absent; when A2 = a single bond, A1 = a double bond and R7 is absent; R1 = (un)substituted heterocyclyl, hetero/aryl; R5 = H, (un)substituted cyclo/alkyl, heterocyclyl, benzyl, hetero/aryl; R6, R7 = independently H, (un)substituted cyclo/alkyl, benzyl; R8-R10 = H, independently (un)substituted alkyl, aryl; and their pharmaceutically acceptable salts and solvates, and their pharmaceutically functional derivs.] were prepd. for use in the manuf. of a medicament for the treatment of a disorder or condition caused by, linked to, or contributed to by, free fatty acids, such as hyperinsulinemia and assocd. conditions, including type 2 diabetes and the like. I are also useful for treating cancer. For example, II was prepd. by reacting Me 2-chloro-3-[3-(trifluoromethyl)phenyl]propanoate (prepn. given) with N-(p-methylphenyl)thiourea. I antagonized the stimulatory effect of free fatty acids on cell proliferation when tested in an assay using a human breast cancer cell line (MDA-MB-231). I attenuated hyperinsulinemia in Ob/Obmice. .