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3733-63-9

Basic Information
CAS No.: 3733-63-9
Name: Decloxizine
Article Data: 5
Molecular Structure:
Molecular Structure of 3733-63-9 (Decloxizine)
Formula: C21H28N2O2
Molecular Weight: 340.466
Synonyms: Decloxizine;NSC 289116;UCB 1402;1-Benzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine;
Density: 1.115 g/cm3
Boiling Point: 472.4 °C at 760 mmHg
Flash Point: 239.5 °C
Appearance: white or similar to white powder
PSA: 35.94000
LogP: 2.27830
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  • 2-(2-(4-Benzhydrylpiperazin-1-yl)ethoxy)ethanol

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    2-(2-(4-Benzhydrylpiperazin-1-yl)ethoxy)ethanol

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    Decloxizine

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    High qualityAppearance:White powder Storage:Room temperature Package:Aluminum bag Application:Used in producing API Transportation:By air Port:Beijing

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  • Ethanol,2-[2-[4-(diphenylmethyl)-1-piperazinyl]ethoxy]-

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    Ethanol,2-[2-[4-(diphenylmethyl)-1-piperazinyl]ethoxy]-

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    Decloxizine

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  • Decloxizine CAS No.3733-63-9

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    Decloxizine CAS No.3733-63-9

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  • Decloxizine

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    Decloxizine

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Chemistry

IUPAC Name: 2-[2-(4-benzhydrylpiperazin-1-yl)ethoxy]ethanol
CAS: 3733-63-9
Formula : C21H28N2O2
Molecular Weight: 340.45922
Molecular Structure of 2-[2-(4-benzhydrylpiperazin-1-yl)ethoxy]ethanol(3733-63-9):

Density: 1.115 g/cm3 
Flash Point: 239.5 °C
Boiling Point: 472.4 °C at 760 mmHg     
Index of Refraction: 1.576 
Molar Refractivity: 101.01 cm3 
Molar Volume: 305.1 cm3 
Polarizability: 40.04× 10-24cm3 
Surface Tension: 46.4 dyne/cm 
Enthalpy of Vaporization: 77.47 kJ/mol  
Vapour Pressure: 9.93E-10 mmHg at 25°C 
Water Solubility: 2459(mg/L) at 25 °C 
Product Categories: pharmaceutical intermediates.

Toxicity Data With Reference

1.    

orl-rat LD50:840 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1002.
2.    

ipr-rat LD50:103 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1002.
3.    

ivn-rat LD50:47 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1002.
4.    

orl-mus LD50:470 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1002.
5.    

ipr-mus LD50:135 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1002.
6.    

ivn-mus LD50:45 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1002.

Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Specification

The chemical synonyms of  2-[2-(4-benzhydrylpiperazin-1-yl)ethoxy]ethanol(3733-63-9) are 1-Benzhydryl-4-(2-(2-hydroxyethoxy)ethyl)piperazine ; Decloxizine ; Decloxizin hydrochloride ; Decloxizine Base ; Decloxazine ; 2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol .