Detail of "3735-98-6"

CAS Number:
3735-98-6
Name:
Phosphonic acid,P-methyl-, ethyl 4-nitrophenyl ester
Molecular Structure:
Formula:
C9H12 N O5 P
Molecular Weight:
0
Synonyms:
Phosphonicacid, methyl-, ethyl 4-nitrophenyl ester (9CI); Phosphonic acid, methyl-, ethylp-nitrophenyl ester (6CI,7CI,8CI); Ethyl 4-nitrophenyl methylphosphonate; Ethylp-nitrophenyl methylphosphonate; O-Ethyl p-nitrophenyl methylphosphonate
Density:
1.298g/cm³
Boiling Point:
356°Cat760mmHg
Flash Point:
169.1°C

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Comparison of three enzymic models for evaluation of reactivators of organophosphorus ester-inhibited acetylcholinesterase: Comparison of three enzymic models for evaluation of reactivators of organophosphorus ester-inhibited acetylcholinesterase. Miller, A.; Nolen, H. W., III; Jackson, S. E.; Howd, R. A.; Harris, R. N., III; Bedford, C. D. (SRI Int., Menlo Park, CA 94025, USA). Proc. West. Pharmacol. Soc., 27, 297-301 (English) 1984. CODEN: PWPSA8. ISSN: 0083-8969. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Reactivation of Et 4-nitrophenyl methylphosphonate (EPMP) [3735-98-6] and 3,3-dimethyl-2-Bu methylphosphonofluoridate (GD) [96-64-0] inhibition of acetylcholinesterase (AChE) [9000-81-1] by imidazole oximes I (R = alkyl or phenylalkyl), 2-PAM [94-63-3], HI-6 [34433-31-3], and toxogonin [114-90-9] (in large excess over EPMP-AChE) restored AChE activity, following a pseudo 1st-order kinetics. Whereas the reactivation of AChE from elec. 3735-98-6 are also occured in this study. eel and bovine and human erythrocytes varied greatly, competitive inhibition by the reactivators was essentially identical across enzyme type. 3735-98-6 is just another one chemical used in this study. I was much more effective in reactivating eel AChE than the mammalian erythrocyte AChE. ..

Specificity of subtilisin Carlsberg in the reaction with O-n-alkyl p-nitrophenyl methylphosphonates: Specificity of subtilisin Carlsberg in the reaction with O-n-alkyl p-nitrophenyl methylphosphonates. Aaviksaar, A.; Peips, M.; Sikk, P. (Inst. Khim. Biol. Fiz., Tallinn, USSR). Eesti NSV Tead. Akad. Toim.Several reagents with their cas registry numbers 3735-98-6 and 10545-71-8 are used here., Keem., 33(1), 62-3 (Russian) 1984. CODEN: ENTKDR. DOCUMENT TYPE: Journal CA Section: 7 (Enzymes) The inhibition of subtilisin Carlsberg (I) by a series of O-n-alkyl O-p-nitrophenyl methylphosphonates, II, in which R is Et through octyl, was studied. As the no. of C atoms in the alkyl chain increased from 2 to 6, the value of the inhibition const., Ki, increased 10-fold (from 0.33 to 3.33 M-1 s-1). Correlations of the inhibitory activity to the hydrophobicity of the compds. were obsd. Max. inhibition of I was obsd. for the C-5 and C-6 alkyl derivs., which had hydrophobic const. values for the alkyl chains of 2.5 and 3, resp. .