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Detail of "3762-25-2"

  • CAS Number:
  • 3762-25-2
  • Name:
  • Phosphonic acid,P-[(4-methylphenyl)methyl]-, diethyl ester

  • Molecular Structure:
  • Formula:
  • C12H19 O3 P
  • Molecular Weight:
  • 242.25
  • Synonyms:
  • Phosphonicacid, (p-methylbenzyl)-, diethyl ester (8CI);Phosphonic acid,[(4-methylphenyl)methyl]-, diethyl ester (9CI);4-Methylbenzylphosphonic aciddiethyl ester;Diethyl (4-methylbenzyl)phosphonate;Diethyl(p-methylbenzyl)phosphonate;Diethyl p-tolylmethylphosphonate;
  • Density:
  • 1.077g/cm3
  • Boiling Point:
  • 341.2°Cat760mmHg
  • Flash Point:
  • 173.9°C
  • Safety:
  • Risk Statements 36/37/38
    Safety Statements 24/25
    WGK Germany 3
    Details

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CAS No.3762-25-2 Phosphonic acid,P-[(4-methylphenyl)methyl]-, diethyl ester

Assay:99.5%  Appearance:powder  Package:25kg/drumStorage:1-10MT

Supplier:Henan Tianfu Chemical Co., Ltd. [ China (Mainland)]

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375Integral
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Tel:86-371-87093236

Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

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CAS No.3762-25-2 Phosphonic acid,P-[(4-methylphenyl)methyl]-, diethyl ester

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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Tel:+86-571-88938639

Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

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CAS No.3762-25-2 Phosphonic acid,P-[(4-methylphenyl)methyl]-, diethyl ester

Assay:99%

Supplier:Tianjin Collabrate Chemical Industry Co.,Ltd [ China (Mainland)]

Manufacturer 1095Integral
1095

Tel:+86-22-63301939

Address:West Industrial park, Dagang District,Tianjin City,China

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CAS No.3762-25-2 Phosphonic acid,P-[(4-methylphenyl)methyl]-, diethyl ester

Supplier:CHEMSWORTH [ India]

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Tel:+91-261-2397244

Address:Unit.133 & 134, Plot 256, Surat Special Economic Zone,Sachin- 394 230

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Reference

Amide bond surrogates: a study in thiophenesulfonamide based endothelin receptor antagonists
Amide bond surrogates: a study in thiophenesulfonamide based endothelin receptor antagonists. Raju, B.; Okun, Ilya; Stavros, Fiona; Chan, Ming Fai ( ImmunoPharmaceutics Inc. (A Wholly-owned Subsidiary of Texas Biotechnology Corp.), San Diego, CA 92127, USA). Bioorganic & Medicinal Chemistry Letters, 7(7), 939-944 (English) 1997 Elsevier. CODEN: BMCLE8. ISSN: 0960-894X.In this article, certain chemicals are used. One of their cas registry numbers is 3762-25-2 DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 27, 28 The potential proteolytic instability of the amide bond present in some ETA selective thiophenesulfonamide endothelin antagonists exemplified by TBC-10708 led the authors to investigate the replacement of this moiety with stable amide bond surrogates such as a trans double bond and an ethylene spacer. The effect of these replacements on the binding affinity is described. .
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