Detail of "37786-00-8"

CAS Number:
37786-00-8
Name:
Prost-13-en-1-oic acid,15-hydroxy-9-oxo-, (13E,15S)-
Molecular Structure:
Formula:
C20H34 O4
Molecular Weight:
338.4816
Synonyms:
(13E)-15-Hydroxy-9-oxoprost-13-enoicacid; 11-Deoxy-PGE1; 11-Deoxyprostaglandin E1; 15(S)-Hydroxy-9-oxo-13-trans-prostenoicacid; AY 23578; Doproston B
Density:
1.07 g/cm³
Boiling Point:
509.7ºC
Flash Point:
276.1 ºC

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Effect of 11-deoxyprostaglandin E1 on hormone balance in an experimental animal study: Effect of 11-deoxyprostaglandin E1 on hormone balance in an experimental animal study. Bergman, A. S.; Ozolina, A.; Freimanis, J.; Veveris, M.; Kimenis, A.; Seglins, A.; Springovich, N. N. (Rizh. Med. Inst., Riga, USSR). Probl. Endokrinol., 30(1), 77-81 (Russian) 1984. CODEN: PROEAS. ISSN: 0375-9660. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) 11-Deoxyprostaglandin E1 (I) [37786-00-8] like PGF2a [551-11-1] showed luteolytic activity in rats and cows and decreased blood progesterone [57-83-0] levels. 551-11-1 and 50-28-2 are just another two chemicals used in this study. I and PGF2a also decreased plasma estradiol [50-28-2] levels in 9-16-day pregnant rats. .

Effect of 11-deoxyprostaglandin E1 on the monoaminergic mechanism of the hypothalamic control of prolactin formation and milk secretion in lactating rats: Effect of 11-deoxyprostaglandin E1 on the monoaminergic mechanism of the hypothalamic control of prolactin formation and milk secretion in lactating rats. Aliev, M. G.; Minh Bien Ha (Inst. Fiziol. im. Karaeva, Baku, USSR). Izv. Akad. Nauk Az. SSR, Ser. Biol. Nauk, (2), 69-73 (Russian) 1984. CODEN: IABLAQ. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) 11-Deoxyprostaglandin E1 (I) [37786-00-8] (20 mg/kg/day, i.m.) administered for 10 days to lactating rats decreased the concns. of dopamine [51-61-6] and noradrenaline [51-41-2] and increased those of serotonin [50-67-9] and 5-HIAA [54-16-0] in the hypothalamus and increased the concns. of prolactin [9002-62-4] and growth hormone [9002-72-6] in the anterior pituitary gland. I also stimulated prolactin secretion and milk secretion and accelerated the growth rate of the pups.