Reference

Cosmetic composition

Cosmetic composition. Ogawa, Yoshikazu (Japan ). Japan. Kokai JP 53052631 13 May 1978 Showa,4 pp. (Japanese). (Japan).Chemical with cas number 9036-88-8 also plays role. CODEN: JKXXAF. CLASS: IC: A61K007-00. APPLICATION: JP 76-127058 22 Oct 1976. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Dried Konjak (Hydrosome rivieri) flour, dried ivory palm seed flour, or purified mannan [9036-88-8] and its derivs., together with amino acids or their derivs. are incorporated into cosmetic dispersions or emulsions for skin, hair or oral application. The prepns. are stable and nonirritating. Thus, a hair lotion was prepd. contg. olive oil 10.0, methylmannan [67724-88-3] 4.0, 0.5% mannan soln. 85.0, N-palmitoyl-L-methionine [36416-81-6] 0.1, L-aspartic acid Me ester [17812-32-7] 1.0, cysteine [52-90-4] 0.3, palmitoyl-L-glutamic acid [38079-66-2] 0.2, and Na L-aspartate [3792-50-5] 0.3 g with preservatives and perfumes added. .

Stabilization of macrolide antibiotics in oral formulations

Stabilization of macrolide antibiotics in oral formulations. (Toyo Jozo Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 59104326 A2 16 Jun 1984 Showa, 35 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K047-00. ICA: A61K031-71. APPLICATION: JP 82-212942 4 Dec 1982. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Oral formulations contain 16-member ring antibiotic macrolides stabilized by one or more stabilizers at pH 3~10. The stabilizers are glycine [56-40-6], glycine aluminum salt [52729-29-0], L-alanine [56-41-7], monosodium glutamate [142-47-2], monosodium aspartate [3792-50-5], etc. Thus, granules consisting of 3''-propionylleucomycin A5 [74014-51-0] 105.3, anhyd. silicic acid 30.0, and hydroxypropyl Me cellulose 7 g were mixed with other granules consisting of glycine 170, citric acid 0~40, anhyd. silicic acid 10, and hydroxypropyl Me cellulose 5 g. To this mixt. were added hydroxypropyl cellulose, Avicel PH-301, and Mg stearate. The mixt. was made into tablets (430 mg/tablet).