Reference

Reaction of 19-hydroxy steroids with diethylaminosulfur trifluoride

Reaction of 19-hydroxy steroids with diethylaminosulfur trifluoride. Ino, Sento; Oinuma, Hisako; Yamakado, Rieko; Morisaki, Masuo; Furukawa, Yoji; Hata, Tadashi (Kyoritsu Coll. Pharm., Tokyo 105, Japan). Chem. Pharm. Bull., 39(12), 3335-7 (English) 1991. CODEN: CPBTAL. ISSN: 0009-2363. DOCUMENT TYPE: Journal CA Section: 32 (Steroids) Reaction of 19-hydroxycholest-4-en-3-one (I) with diethylaminosulfur trifluoride in acetonitrile at reflux gave 10b-fluoro-5,10-seco-5,19-cyclocholest-4-en-3-one (II) in 60% yield. Analogous reactions of anhydrostane derivs. III (X = O; a-H,b-OH) afforded the corresponding bicyclo[4.4.1] compds.In this experiment, several chemicals are used like 38078-09-0 and 6678-08-6 IV (X same). Under milder reaction conditions, the diethylaminosulfinate V was secured in 20% yield from I. .

Preparation of fluorolactones from the reaction of g-ketoacids with diethylaminosulfur trifluoride

Preparation of fluorolactones from the reaction of g-ketoacids with diethylaminosulfur trifluoride. Patrick, Timothy B.; Poon, Yam Foo (Dep. Chem., South. Illinois Univ., Edwardsville, IL 62026, USA). Tetrahedron Lett., 25(10), 1019-22 (English) 1984. CODEN: TELEAY. 38078-09-0 is also in the experiment. ISSN: 0040-4039. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Levulinic acid and related g-keto acids reacted with diethylaminosulfur trifluoride to give g-fluorobutyrolactones I and II (R = Ph, Me) in good yield. The involvement of a bicyclic (3.2.1) mechanism is considered. .