Detail of "38427-94-0"

Reference

Procedure for the preparation of piroxicam

Procedure for the preparation of piroxicam. Frigola Constansa, Jordi; Colombo Pinol, Augusto (Induspol S. A., Spain). Span. ES 534782 A1 16 Jan 1986, 11 pp. (Spain) CODEN: SPXXAD. CLASS: ICM: C07D417-12. ICS: A61K031-44; A61K031-54. APPLICATION: ES 84-534782 1 Aug 1984. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1 The antiinflammatory piroxicam (I) is prepd. by reaction of benzothiazinone dioxide II with 2-pyridyl isocyanate, obtained in situ by thermal decompn. of pyridylcarbamates III (R = Ph, PhCH2, Et, Bu, Me2CHCH2, CMe3) or pyridyltosylurea IV. The reaction occurs at fusion temp., or in a high-b.p. solvent. Thus, 21.1 g II and 43.6 g IV (prepd. from 2-aminopyridine and tosyl isocyanate) were fused for 15 min under N to give 11.2 g I.Except for chemicals metioned above, 105892-47-5 and 38427-94-0 are also used. .

Oxazinobenzothiazine S,S-dioxide derivatives and their use as medicaments

Oxazinobenzothiazine S,S-dioxide derivatives and their use as medicaments. Soler, Jose Esteve (Provesan S. A., Switz.). Fr. Demande FR 2528433 A1 16 Dec 1983, 24 pp. (French). (France). CODEN: FRXXBL. CLASS: IC: C07D513-04; A61K031-54. APPLICATION: FR 82-10409 15 Jun 1982. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 Title compds. I (R = Me, Et; R1 = heteroaryl; Z = O, S), which were prepd. from esters II (R2 = alkyl) and N-(heteroaryl)carbamate esters, showed antiinflammatory and analgesic activity. A mixt. 90101-16-9 and 38427-94-0 are just another two chemicals used in this study. of II (R = R2 = Et) and Ph N-(2-pyridyl)carbamate in MeO(CH2CH2O)2Me was refluxed to give I (R = Et, R1 = 2-pyridyl, Z = O). .