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CAS No.: | 38748-32-2 |
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Name: | Triptolide |
Article Data: | 9 |
Molecular Structure: | |
Formula: | C20H24O6 |
Molecular Weight: | 360.407 |
Synonyms: | (-)-Triptolide;NSC 163062;PG 490;[3bS-(3ba,4aa,5aR*,6b,6ab,7ab,7ba,8aR*,8bb)]-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one; |
EINECS: | 300-006-3 |
Density: | 1.48 g/cm3 |
Melting Point: | 226-227 °C |
Boiling Point: | 601.7 °C at 760 mmHg |
Flash Point: | 220.7 °C |
Solubility: | soluble in DMSO |
Appearance: | White crystalline solid |
Safety: | 22-24/25 |
PSA: | 84.12000 |
LogP: | 1.10310 |
Name : Triptolide
Molecular Structure :
Molecular Formula : C20H24O6
Molecular Weight : 360.41
CAS Registry Number : 38748-32-2
storage temp : 2-8°C
form : solid
solubility :soluble
color :white to off-white
Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Triptolide is a potent, biologically active compound isolated from the medicinal 'Thunder God Vine' Tripterygium wilfordii Hook F. The TCM tea Lei Gong Teng made from this plant has been used for centuries, as a therapeutic against cancer, inflammation, and auto-immune diseases. Crews and colleagues showed that triptolide causes cell growth arrest in certain cell types.
Diterpenoid triepoxide with immunosuppressant
antitumor properties
1. | ipr-mus LD50:900 µg/kg | CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70. | ||
2. | ivn-mus LD50:800 µg/kg | CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70. | ||
3. | ivn-dog LDLo:160 µg/kg | CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70. |