Detail of > 389-08-2
- CAS Number:
- 389-08-2
- Name:
1,8-Naphthyridine-3-carboxylicacid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-
- Superlist Name:
- Nalidixic acid
- Formula:
- C12H12N2O3
- Molecular Structure:

- Synonyms:
- 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicacid;1-Ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid;1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid;3-Carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one;Betaxina;Dixiben;Eucistin;Innoxalomn;Nalidicron;Nalidixan;Nalidixin;Nalitucsan;Nalurin;Nelidix;Nevigramon;Poleon;Specifin;Urisal;Uroman;Wintomylon;
- Molecular Weight:
- 232.23
- EINECS:
- 206-864-7
- Density:
- 1.331 g/cm3
- Melting Point:
- 227-229 °C(lit.)
- Boiling Point:
- 413.1 °C at 760 mmHg
- Flash Point:
- 203.6 °C
- Solubility:
- 0.1 g/L (23 °C) in water
- Appearance:
- crystalline powder
- Hazard Symbols:
Xn- Risk Codes:
- 63-42/43-40-20/21/22
- Safety:
- 22-36/37-45-24-36Details
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Reference
- Effects of oxolinic acid on the sweetfish in Lake Hamana, Japan
- Effects of oxolinic acid on the sweetfish in Lake Hamana, Japan. Ai, Takao; Ushiyama, Munehiro (Suisan Shikenjo, Japan). Shizuoka-ken Suisan Shikenjo Jigyo Hokoku, Volume Date 1973 171-2 (Japanese) 1974. CODEN: SSJHAI. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Oxolinic acid (I) [14698-29-4] added to a culture medium of sweetfish at 2 ppm prevented the occurrence of Vibrio infection, but nalidixic acid [389-08-2] similarly used was not effective.
- Changes in the ratio of activity of reparative and replicative enzymes of DNA synthesis as a basis for the search for radioprotective drugs
- Changes in the ratio of activity of reparative and replicative enzymes of DNA synthesis as a basis for the search for radioprotective drugs. Filippovich, I. V.; Romantsev, E. F. (Inst. Biophys., Moscow, USSR). Modif. Radiosensitivity Biol. Syst., Proc. Advis. Group Meet., Meeting Date 1975, 205-6. IAEA: Vienna, Austria. (English) 1976. CODEN: 35WGA2. DOCUMENT TYPE: Conference CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 8 Preincubation of thymocytes with specific inhibitors of replication DNA polymerase [9012-90-2] [nalidixic acid (I) [389-08-2] or 1-.beta.-D-arabinofuranosylcytosine [147-94-4]] protected the cells against radiation damage. The effect was attributed to temporary inhibition of DNA replication while DNA repair proceded.
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