CAS No.3930-20-9,Sotalol Suppliers

Products Categories

Pharmaceutical (20)
Others (6)
Organic Chemicals (6)
Reagent (3)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	3930-20-9
Name:	Sotalol
Article Data:	2

Formula:	C₁₂H₂₀N₂O₃S
Molecular Weight:	272.368
Synonyms:	Methanesulfonanilide,4'-[1-hydroxy-2-(isopropylamino)ethyl]- (8CI);4'-[1-Hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide;Beta-Cardone;DL-4-(2-Isopropylamino-1-hydroxyethyl)methanesulfonanilide;
Density:	1.24 g/cm³
Melting Point:	206.5-207 °C
Boiling Point:	443.3 °C at 760 mmHg
Flash Point:	221.9 °C
Appearance:	white crystalline
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	26-36
PSA:	86.81000
LogP:	2.63420

Total:35 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 3930-20-9

Specification

The Sotalol with the cas number 3930-20-9, is also called Methanesulfonamide, N-(4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)phenyl)-. The systematic name is N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide. Its molecular formula is C₁₂H₂₀N₂O₃S. This chemical is white crystalline.

The properties of the chemical are: (1)ACD/LogP: 0.32; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.7; (4)ACD/LogD (pH 7.4): -1.56; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 5; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 58.23 Å²; (13)Index of Refraction: 1.57; (14)Molar Refractivity: 72.13 cm³; (15)Molar Volume: 219.7 cm³; (16)Polarizability: 28.59×10^-24cm³; (17)Surface Tension: 50.6 dyne/cm; (18)Enthalpy of Vaporization: 73.87 kJ/mol; (19)Vapour Pressure: 1.22×10^-8mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following: (1)Irritating to eyes, respiratory system and skin; (2)In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; (3)Wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: O=S(=O)(Nc1ccc(cc1)C(O)CNC(C)C)C
(2)InChI: InChI=1/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	3429ug/kg/2D- (3.429mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Australian and New Zealand Journal of Medicine. Vol. 24, Pg. 319, 1994.
mouse	LD50	intraperitoneal	790mg/kg (790mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Polish Journal of Pharmacology and Pharmacy. Vol. 25, Pg. 145, 1973.
mouse	LD50	intravenous	113mg/kg (113mg/kg)		United States Patent Document. Vol. #5118689,
women	LDLo	oral	288mg/kg (288mg/kg)	BEHAVIORAL: COMA CARDIAC: CHANGE IN RATE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Journal of Toxicology, Clinical Toxicology. Vol. 26, Pg. 389, 1988.
women	TDLo	multiple routes	100mg/kg/2W-I (100mg/kg)	CARDIAC: OTHER CHANGES	American Heart Journal. Vol. 107, Pg. 179, 1984.
women	TDLo	oral	14mg/kg/3D-I (14mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP CARDIAC: PULSE RATE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Australian and New Zealand Journal of Medicine. Vol. 24, Pg. 319, 1994.
women	TDLo	oral	118mg/kg/4W-I (118mg/kg)	CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE CARDIAC: PULSE RATE CARDIAC: CHANGE IN RATE	Postgraduate Medical Journal. Vol. 68, Pg. 289, 1992.