Products Categories
| CAS No.: | 3978-81-2 |
|---|---|
| Name: | 4-tert-Butylpyridine |
| Article Data: | 40 |
| Molecular Structure: | |
|
|
|
| Formula: | C9H13N |
| Molecular Weight: | 135.209 |
| Synonyms: | Pyridine,4-(1,1-dimethylethyl)-;Pyridine,4-tert-butyl- (6CI,7CI,8CI);4-(1,1-Dimethylethyl)pyridine;4-t-Butylpyridine;NSC 5104;p-tert-Butylpyridine; |
| EINECS: | 223-614-2 |
| Density: | 0.905 g/cm3 |
| Melting Point: | -40°C(lit.) |
| Boiling Point: | 197.1 °C at 760 mmHg |
| Flash Point: | 63.3 °C |
| Solubility: | Practically insoluble in water |
| Appearance: | clear colorless to slightly yellow liquid |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36 |
| PSA: | 12.89000 |
| LogP: | 2.37910 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
- 43224-75-52,2,6,6-Tetramethyl-4-(2-propyleneoxy) Piperidine
- 23569-17-7
4-tert-butylpyridine N-oxide
- 3978-81-2
4-tert-butylpyridine
| Conditions | Yield |
|---|---|
| With titanium tetrachloride; tin(ll) chloride In benzene for 0.5h; Ambient temperature; | 99% |
| With ammonium formate; palladium on activated charcoal In methanol for 0.166667h; Ambient temperature; | 97% |
| With sodium hypophosphite; palladium on activated charcoal In acetic acid at 60℃; for 1h; | 97% |
- 34995-29-4
1-chloro-2-methyl-2-(4-pyridyl)propane
- 3978-81-2
4-tert-butylpyridine
| Conditions | Yield |
|---|---|
| With lithium In tetrahydrofuran a) 0 deg C, 90 min, b) 25 deg C, 4 h; | 91% |
- 594-19-4
tert.-butyl lithium
- 181219-01-2
4-pyridineboronic acid pinacol ester
- 3978-81-2
4-tert-butylpyridine
| Conditions | Yield |
|---|---|
| Stage #1: tert.-butyl lithium; 4-pyridineboronic acid pinacol ester In tetrahydrofuran at -78 - 20℃; for 0.833333h; Inert atmosphere; Stage #2: With trifluoroacetyl chloride In tetrahydrofuran at -78 - 40℃; for 15.5h; Inert atmosphere; Further stages; | 85% |
- 23569-17-7
4-tert-butylpyridine N-oxide
- 16420-13-6
N,N-Dimethylthiocarbamoyl chloride
A
- 3978-81-2
4-tert-butylpyridine
| Conditions | Yield |
|---|---|
| In acetonitrile at 81℃; for 4h; | A 81% B 4% |
- 38442-51-2
tert-butylmercury chloride
- 22581-65-3
1-Methoxypyridinium iodide
A
- 3978-81-2
4-tert-butylpyridine
B
- 5944-41-2
2-tert-butylpyridine
C
- 29939-31-9
2,4-di-tert-butylpyridine
| Conditions | Yield |
|---|---|
| With potassium iodide In dimethyl sulfoxide at 35 - 40℃; for 0.5h; Irradiation; | A 71% B 23% C n/a |
- 3978-81-2
4-tert-butylpyridine
| Conditions | Yield |
|---|---|
| With 2,2'-azobis(isobutyronitrile) In tetrahydrofuran for 72h; Heating; | 55% |
- 100-48-1
pyridine-4-carbonitrile
- 84379-72-6
1,3-dioxoisoindolin-2-yl 3,3-dimethylbutanoate
- 3978-81-2
4-tert-butylpyridine
| Conditions | Yield |
|---|---|
| Stage #1: pyridine-4-carbonitrile; 1,3-dioxoisoindolin-2-yl 3,3-dimethylbutanoate With bis(pinacol)diborane; zinc(II) chloride In tert-butyl methyl ether at 80℃; for 24h; Stage #2: With sodium carbonate In water regioselective reaction; | 35% |
| Conditions | Yield |
|---|---|
| With ammonia; sodium amide |
- 110-86-1
pyridine
- 38442-51-2
tert-butylmercury chloride
A
- 3978-81-2
4-tert-butylpyridine
B
- 5944-41-2
2-tert-butylpyridine
| Conditions | Yield |
|---|---|
| With 1,4-diaza-bicyclo[2.2.2]octane at 40℃; for 5h; Irradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
- 110-86-1
pyridine
- 89379-02-2
tert-butylmercury iodide
A
- 3978-81-2
4-tert-butylpyridine
B
- 5944-41-2
2-tert-butylpyridine
| Conditions | Yield |
|---|---|
| With toluene-4-sulfonic acid; potassium iodide In dimethyl sulfoxide Irradiation; |
- 10396-10-8p-Toluenesulfonyl semicarbazide
- 11141-17-61H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylicacid,10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]o
- 1907-33-1Lithium tert-butoxide
- 2231-57-4Thiocarbohydrazide
- 2425-79-81,4-Butane diglycidyl ether
- 2189-60-81-Phenyloctane
- 70-26-8L-Ornithine
- 84434-11-7Ethyl (2,4,6-trimethylbenzoyl) phenylphosphinate
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Specification
The CAS register number of 4-tert-Butylpyridine is 3978-81-2. It also can be called as Pyridine, 4-tert-butyl-; 4-(t-Butyl)pyridine; p-tert-Butyl pyridine. The molecular formula about this chemical is C9H13N and the molecular weight is 135.21. It belongs to the following product categories which include C9 to C46; Heterocyclic Building Blocks; Pyridines and so on.
Physical properties about 4-tert-Butylpyridine are: (1)ACD/LogP: 2.741; (2)ACD/LogD (pH 5.5): 2.14; (3)ACD/LogD (pH 7.4): 2.73; (4)ACD/BCF (pH 5.5): 17.81; (5)ACD/BCF (pH 7.4): 68.74; (6)ACD/KOC (pH 5.5): 184.33; (7)ACD/KOC (pH 7.4): 711.29; (8)#H bond acceptors: 1; (9)#Freely Rotating Bonds: 1; (10)Index of Refraction: 1.484 ; (11)Molar Refractivity: 42.731 cm3; (12)Molar Volume: 149.345 cm3; (13)Polarizability: 16.94 10-24cm3; (14)Surface Tension: 29.9799995422363 dyne/cm; (15)Density: 0.905 g/cm3; (16)Flash Point: 63.333 °C; (17)Enthalpy of Vaporization: 41.558 kJ/mol; (18)Boiling Point: 197.095 °C at 760 mmHg; (19)Vapour Pressure: 0.541999995708466 mmHg at 25°C
Preparation of 4-tert-Butylpyridine: this chemical can be prepared by 4-tert-butyl-pyridine 1-oxide. This reaction will need reagent aq. NaOH, thiourea S,S-dioxide and solvent ethanol. The reaction time is 1 hour(s) with reaction temperature of 80 - 85 °C. The yield is about 84%.
(1).jpg)
Uses of 4-tert-Butylpyridine: it can be used to produce N-(2',4'-dinitrophenyl)-4-tert-butylpyridinium chloride with 1-chloro-2,4-dinitro-benzene at heating. This reaction is a kind of Arylation. It will need solvent acetone with reaction time of 12 hours. The yield is about 72%.
.jpg)
When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1)SMILES: n1ccc(cc1)C(C)(C)C
(2)InChI: InChI=1/C9H13N/c1-9(2,3)8-4-6-10-7-5-8/h4-7H,1-3H3
(3)InChIKey: YSHMQTRICHYLGF-UHFFFAOYAN
(4)Std. InChI: InChI=1S/C9H13N/c1-9(2,3)8-4-6-10-7-5-8/h4-7H,1-3H3
(5)Std. InChIKey: YSHMQTRICHYLGF-UHFFFAOYSA-N
-
Premium Related Products
