Detail of "4005-51-0"

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CAS Number:
4005-51-0
Name:
2-Amino-1,3,4-thiadiazole
Molecular Structure:
Formula:
C₂H₃N₃S
Molecular Weight:
101.13
Synonyms:
1,3,4-Thiadiazole,2-amino- (6CI,7CI,8CI);1,3,4-Thiadiazol-2-ylamine;1,3,4-Thiadiazole-2-amine;2-Aminothiadiazole;5-Amino-1,3,4-thiadiazole;Aminothiadiazole;NSC 4728;TF 128;
EINECS:
223-657-7
Density:
1.495 g/cm³
Melting Point:
181-182 °C
Boiling Point:
238.9 °C at 760 mmHg
Flash Point:
98.3 °C
Appearance:
white to light yellow crystal powder
Hazard Symbols:
Xn, Xi
Risk Codes:
68-63-36/37/38-20/21/22-22
Safety:
36/37/39-26-36 Details
Transport Information:
UN 2811

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Reference

Effect of 2,2'-(methylenediimino)bis(1,3,4-thiadiazole) and 2-amino-1,3,4-thiadiazole on sister chromatic exchange (SCE) frequency in cultured cells: Effect of 2,2'-(methylenediimino)bis(1,3,4-thiadiazole) and 2-amino-1,3,4-thiadiazole on sister chromatic exchange (SCE) frequency in cultured cells. Fu, Zhongzhen; Xu, Weiguang; Wang, Ruishu; Peng, Shusheng (Dep. Hyg., Sichuan Med. Coll., Chengdu, Peop. Rep. China). Xibao Shengwuxue Zazhi, 5(2), 33-6 (Chinese) 1983. CODEN: XISZD3. ISSN: 0253-9977. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) SCE frequency in cultured CHO-K1 cells was increased by treatment with 2,2'-(methylenediimino)bis(1,3,4-thiadiazole) (I) [26907-37-9] or 2-amino-1,3,4-thiadiazole (II) [4005-51-0]; such increases could be antagonized with NAD. SCE was 7.72-8.52/cell in control but it was 22.48/cell in 2.0 mM I and 16.60/cell in 500 mM II. The mode of action of I and II on SCE may be through inhibiting IMP dehydrogenase.

A sensitive method for the determination of residues of N,N'-bis(1,3,4-thiadiazol-2-yl)methanediamine in rice: A sensitive method for the determination of residues of N,N'-bis(1,3,4-thiadiazol-2-yl)methanediamine in rice. Hsueh, Weiling; Liu, Yuling; Fan, Tie (Sichuan Res. Inst. Pestic., Chin. Acad. Agric. Sci., Chongqing, Peop. Rep. China). Pestic. Sci., 16(1), 59-64 (English) 1985. CODEN: PSSCBG. ISSN: 0031-613X. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Section cross-reference(s): 4 A sensitive method for the isolation, clean-up, and TLC semi-quant. detn. of residues of N,N'-bis(1,3,4-thiadiazol-2-yl)methanediamine (I) [26907-37-9] in rice is reported. The residue from I in rice was its degrdn. product 1,3,4-thiadiazol-2-ylamine (II) [4005-51-0]. The mean recovery by this method was 85%, and the lowest limit of detn. was 0.01 mg/kg. Using this proposed technique, the residues of II and I in various field-treated rice samples were studied.

Detail of "4005-51-0"

2-Amino-1,3,4-thiadiazole

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Reference