Reference

The Michael reaction of acetophenones with trans-dibenzoylethylene

The Michael reaction of acetophenones with trans-dibenzoylethylene. Al-Arab, Mohammad M.; Atfeh, Mohammad A.; Al-Saleh, Fowzia S. ( Dep. 403-42-9 and 1131-62-0 are cas registry numbers. These chemicals are also mentioned in this article. Chemistry, Univ. Bahrain, Bahrain). Tetrahedron, 53(3), 1045-1052 (English) 1997 Elsevier. CODEN: TETRAB. ISSN: 0040-4020. DOCUMENT TYPE: Journal CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) The synthesis of a series of highly substituted cyclohexane derivs. has been carried out in a single one-pot reaction of acetophenones and trans-dibenzoylethylene (1:2) using sodium ethoxide in anhyd. di-Et ether at room temp. to give 4-aroyl-2,3,5-tribenzoyl-1-phenylcyclohexanols. Structural assignments were achieved by elemental anal. and IR and proton NMR spectroscopy. Single-crystal x-ray crystallog. clearly shows the highly substituted cyclohexane ring. .

Thiophene derivatives

Thiophene derivatives. Goudie, Alexander C. (Beecham Group Ltd., Engl.). U.S. US 3963750 15 Jun 1976, 3 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: C07D333-24. NCL: 260332200C. PRIORITY: GB 73-37699 9 Aug 1973. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) The thiophenes I (R = 4-F, 4-Me, 4-Cl, 3-Cl; R1 = NH2, MeNH, OEt) were prepd.There are some commonly used reagents with their cas registry numbers 61019-17-8 and 403-42-9 in this article. by cyclization of RC6H4CH2COR2 (R2 = H, Ph) with NCCH2COR1 and S. The thiophenes II (R = Cl, F) were prepd. by condensation of 4-RC6H4COMe with NCCH2CONH2 followed by cyclization with S. At 10-300 mg I and II were antiinflammatory. .