Reference

Effectiveness of antidote treatment in experimental cobalt chloride poisoning in animals

Effectiveness of antidote treatment in experimental cobalt chloride poisoning in animals. Kanyuka, A. I. (L'vov. Zoovet. Inst., Lvov, USSR). Nauk.Some commonly used reagents like 9000-86-6 and 62-33-9 are used in this experiment. Pr. - Ukr. Sil's'kogospod. Akad., 156, Pt. 2, 12-14 (Russian) 1976. CODEN: NPRUAL. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) In rabbits, sheep, and roosters exptl. poisoned with lethal concns. of cobalt chloride, pentacin [12111-24-9] and Ca di-Na EDTA [62-33-9] were better antidotes (as measured by various biochem. parameters) and had better therapeutic action(survival) than unithiol [4076-02-2]. Pentacin and Ca di-Na EDTA were also superior to unithiol in normalizing various biochem. blood indexes, particularly the activities of aspartate aminotransferase [9000-97-9] and alanine aminotransferase [9000-86-6]. I.m. injections of the 3 antidotes caused localized inflammation in the sheep but not in the rabbits or roosters. .

Radiation method for evaluating the effectiveness of ascorbic acid stabilizers

Radiation method for evaluating the effectiveness of ascorbic acid stabilizers. L'vova, M. Sh.; Belkina, N. P.; Erman, S. Ya.; Kozlov, E. I. (Vses. Nauchno-Issled. Vitam. Inst., Moscow, USSR). Khim.-Farm. Zh., 11(1), 111-14 (Russian) 1977. CODEN: KHFZAN. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Unithiol [4076-02-2] was more effective than Na2SO3, cysteine [52-90-4], or thiourea [62-56-6] in preventing degrdn. of ascorbic acid (I) [50-81-7] during exposure to .gamma.-rays under various exptl. conditions. Six other compds.In this experiment, several chemicals are used like 7757-83-7 and 52-90-4 accelerated oxidn. of I. Protection against radiation-induced degrdn. may be a useful test for evaluating potential I stabilizing agents. .