Reference

General methods for enriching aldoses with oxygen isotopes

General methods for enriching aldoses with oxygen isotopes. Clark, Edward L., Jr.; Barker, Robert (Div. Biol. Sci., Cornell Univ., Ithaca, NY 14853, USA). Carbohydr. Res., 153(2), 253-61 (English) 1986. CODEN: CRBRAT. ISSN: 0008-6215. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) The general approach for enriching 4-, 5-, and 6-carbon aldoses with oxygen isotopes includes exchange between H218O and the aldehyde group of an aldose, exchange of 0-1 onto C-2 of both of the 2-epimeric aldoses formed by molybdate-resin epimerization, and chain extension using cyanide addn. These methods make possible the prodn. of all 16 aldohexoses enriched at 5 of the 6 oxygen atoms, all 8 aldopentoses enriched at 4 of the 5 oxygen atoms, and the four aldotetroses enriched at 2 of the 4 oxygen atoms. The general applicability of these methods is illustrated by the synthesis of a group of 22 different, 18O-enriched, biol. important D-aldoses having 4, 5, and 6 carbon atoms. The group includes D-[1-, 2-, 3-, 4-, and 6-18O]glucose, D-[1-, 2-, 3-, 4-, and 6-18O]mannose, D-[1-, 2-, 3-, and 5-18O]arabinose, D-[1- and 2-18O]erythrose, and D-[1- and 2-18O]threose. The gas chromatog.In this experiment, several chemicals are used like 108273-99-0 and 4099-85-8 -mass spectral characterization of these sugars with respect to the position and degree of 18O-enrichment is reported. The potential of the methods for producing aldoses having oxygen labels at multiple positions, or aldoses labeled simultaneously with oxygen, hydrogen, and carbon isotopes is discussed. .

Solid-phase synthesis of a fragment of the capsular polysaccharide of Hemophilus influenzae type B using H-phosphonate intermediates

Solid-phase synthesis of a fragment of the capsular polysaccharide of Hemophilus influenzae type B using H-phosphonate intermediates. Nilsson, Stinabritt; Bengtsson, Marita; Norberg, Thomas (Org. Synth. Dep., BioCarb Technol.Several substances are used for example 4099-85-8 which is its cas registry number. 4099-85-8 is the cas registry number of certain chemical which is used as reagents here. AB, Lund S-223 70, Swed.). J. Carbohydr. Chem., 11(3), 265-85 (English) 1992. CODEN: JCACDM. ISSN: 0732-8303. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) Oligosaccharide fragment I of the capsular polysaccharide of Haemophilus influenzae type b, contg. a linker group, was synthesized by a simple solid-phase procedure. Cross-linked polystyrene was used as a solid phase, and a benzyl-protected ribosylribitol H-phosphonate was used as monomer. A non-promoted glycosidation reaction was used for prepn. of the ribosylribitol monomer. ..