Reference

Reactions of 1,4-dinitroimidazoles with hydrazines

Reactions of 1,4-dinitroimidazoles with hydrazines. Suwinski, Jerzy; Szczepankiewicz, Wojciech (Inst. Org. Chemistry Technology, Silesian Technical Univ., Gilwice 44-100, Pol.). Tetrahedron, 52(47), 14905-14916 (English) 1996 Elsevier. CODEN: TETRAB. 302-01-2 and 4319-49-7 which are cas registry numbers are also used here. ISSN: 0040-4020. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 22, 72 Reaction of 2-methyl-1,4-dinitroimidazole with hydrazine resulted in the expansion of the imidazole ring and formation of 3-methyl-1,2,4-triazin-5(2H)-one (3-methyl-1,2,4-triazin-5(2H)-ylidene)hydrazone toluenesulfonate (I). Reaction of 1,4-dinitroimidazole with N-aminomorpholine gave 1-(N-morpholino)-4-nitroimidazole, by degenerative transformation of the imidazole ring. Treatment of 1,4-dinitroimidazoles with t-butoxycarbonylhydrazine resulted in the break down of the imidazole ring and formation of glyoxal dihydrazone derivs. Structures of representative heterocyclic products were detd. by x-ray anal. .

N-Aminomorpholine

N-Aminomorpholine. Oniscu, Corneliu; Surpateanu, Gheorghe; Horoba, Eugen Vasile; Apan, Rodica; Muresan, Corina Mariana (Institutul Politehnic, Iasi, Rom.). Rom. RO 88973 B1 30 Apr 1986, 2 pp. (Romania) CODEN: RUXXA3. CLASS: ICM: C07D295-04. ICS: C07D265-30. APPLICATION: RO 84-115232 14 Jul 1984. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 63 The title compd. 4319-49-7 and 59-89-2 which are cas registry numbers of chemicals are mentioned. (I), useful as intermediate for cardiovascular agents, was prepd. by redn. of nitrosomorpholine with Al amalgam, in (Et)2O at pH 8 and -5 to 0° for 3-4 h. .