Detail of "4439-83-2"

CAS Number:
4439-83-2
Name:
Norvaline, 4-oxo-
Molecular Structure:
Formula:
C₅H₉NO₃
Molecular Weight:
131.12986
Synonyms:
Levulinic acid, 2-amino- (7CI,8CI);2-Amino-4-ketopentanoicacid;2-Amino-4-oxopentanoic acid;a-Aminolevulinic acid;
Density:
1.227 g/cm³
Boiling Point:
289.142 °C at 760 mmHg
Flash Point:
128.669 °C

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Effect of small amounts of lead on workers: Effect of small amounts of lead on workers. Simaitis, R.; Ciuniene, E. (Inst. Epidemiol., Mikrobiol. Gig., Vilnius, USSR). Gig. Tr. Prof. Zabol., (12), 50-3 (Russian) 1977. CODEN: GTPZAB. DOCUMENT TYPE: Journal CA Section: 59 (Air Pollution and Industrial Hygiene) Section cross-reference(s): 14 Anal. of air from work areas for soldering app. and instruments, and blood tests, showed that prolonged exposure to Pb at concns. near the max. permissible concn. increases excretion of a-aminolevulinic acid (I) [4439-83-2] with creatinine (II) in urine from 0.27 mg I/g II in controls to 5.0 in workers with >11 yr service. The activity of ornithine carbamoyltransferase [9001-69-8] in blood serum also increases with increasing service, providing, together with execretion of I, the most sensitive indicators of Pb poisoning.

Concentration of d-aminolevulinic acid in the urine of cows exposed to lead stress from feed under normal farming conditions in the West-Slovakian Region: Concentration of d-aminolevulinic acid in the urine of cows exposed to lead stress from feed under normal farming conditions in the West-Slovakian Region. Szaboova, Eva; Gajdosik, Dusan (Statny Vet. Ustav, Nitra 949 01, Czech.). Vet. Med. (Prague), 31(11), 659-68 (Czech) 1986.Chemicals with cas numbers 7439-92-1 and 4439-83-2 also play role. CODEN: VTMDAR. ISSN: 0375-8427. DOCUMENT TYPE: Journal CA Section: 13 (Mammalian Biochemistry) Section cross-reference(s): 4, 17 In samples of urine from herds of healthy dairy cows from relatively nonpolluted regions of western Slovakia collected in Sept.-Nov., 1984, the av. concns. of d-aminolevulinic acid (ALA) in urine were 42.7 mM or 36.8 mmol/g creatinine, 95% of the samples had values <105 mM urine. The av. Pb concn. in feed and the daily intake with feed were 5.8 mg/kg feed and 0.157 mg/kg body wt., resp. Apparently, the obsd. ALA concns. in urine are physiol. values; ALA concns. in urine of >105 mM may indicate increased Pb intake. .